ID A0A183CNW6_GLOPA Unreviewed; 1617 AA.
AC A0A183CNW6;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=ATP-dependent DNA helicase {ECO:0000256|RuleBase:RU363044};
DE EC=3.6.4.12 {ECO:0000256|RuleBase:RU363044};
OS Globodera pallida (Potato cyst nematode).
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Tylenchina; Tylenchomorpha; Tylenchoidea; Heteroderidae; Heteroderinae;
OC Globodera.
OX NCBI_TaxID=36090 {ECO:0000313|Proteomes:UP000050741, ECO:0000313|WBParaSite:GPLIN_001457300};
RN [1] {ECO:0000313|Proteomes:UP000050741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lindley {ECO:0000313|Proteomes:UP000050741};
RA Aslett M.;
RL Submitted (DEC-2013) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Proteomes:UP000050741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Lindley {ECO:0000313|Proteomes:UP000050741};
RA Cotton J.A., Lilley C.J., Jones L.M., Kikuchi T., Reid A.J., Thorpe P.,
RA Tsai I.J., Beasley H., Blok V., Cock P.J.A., Van den Akker S.E.,
RA Holroyd N., Hunt M., Mantelin S., Naghra H., Pain A., Palomares-Rius J.E.,
RA Zarowiecki M., Berriman M., Jones J.T., Urwin P.E.;
RT "The genome and life-stage specific transcriptomes of Globodera pallida
RT elucidate key aspects of plant parasitism by a cyst nematode.";
RL Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases.
RN [3] {ECO:0000313|WBParaSite:GPLIN_001457300}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|RuleBase:RU363044};
CC -!- SIMILARITY: Belongs to the helicase family.
CC {ECO:0000256|RuleBase:RU363044}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR WBParaSite; GPLIN_001457300; GPLIN_001457300; GPLIN_001457300.
DR Proteomes; UP000050741; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:RHEA.
DR GO; GO:0003678; F:DNA helicase activity; IEA:InterPro.
DR GO; GO:0006310; P:DNA recombination; IEA:UniProtKB-KW.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0000723; P:telomere maintenance; IEA:InterPro.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR010285; DNA_helicase_pif1-like.
DR InterPro; IPR025476; Helitron_helicase-like.
DR InterPro; IPR003323; OTU_dom.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR049163; Pif1-like_2B_dom.
DR PANTHER; PTHR10492:SF57; ATP-DEPENDENT DNA HELICASE; 1.
DR PANTHER; PTHR10492; UNCHARACTERIZED; 1.
DR Pfam; PF14214; Helitron_like_N; 1.
DR Pfam; PF05970; PIF1; 1.
DR Pfam; PF21530; Pif1_2B_dom; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS50802; OTU; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|RuleBase:RU363044};
KW DNA damage {ECO:0000256|RuleBase:RU363044};
KW DNA recombination {ECO:0000256|RuleBase:RU363044};
KW DNA repair {ECO:0000256|RuleBase:RU363044};
KW Helicase {ECO:0000256|RuleBase:RU363044};
KW Hydrolase {ECO:0000256|RuleBase:RU363044};
KW Nucleotide-binding {ECO:0000256|RuleBase:RU363044}.
FT DOMAIN 1540..1617
FT /note="OTU"
FT /evidence="ECO:0000259|PROSITE:PS50802"
FT REGION 1447..1523
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1495..1523
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1617 AA; 183456 MW; 303624E4FAFAED64 CRC64;
XNELLELLHR LLSHQQIGHP LSGLYFHLKR VYEEARQQQA DCDGPPVDNL RIRLLTRGEV
MQQHLPEAHN IHPHQLQLPE SVNQLAQIFF VDGDDGLPPA AEQGVMMKTR SGALTVLPWW
DNWIDGALCP LLFPCGGSVW KPSLPLTTPD SAASLPQQQS RIESEEQHVV PVLAGDDVEW
QNNPYADEAE DILAEADDDG EGEQLLLEAE PKKPHHVSRS QAARYMMQVR APPRHPGHQQ
RNPWHDPHWL WWARRLAEFF VCLLSNRIDR DKFANIKKNQ PEQRSILPAH LVRHFEREAQ
KQLDRQGQPL GERAQLGRIF LAPRTLRGSR AYYQLQFADA MAICRQLGAP HLLITFTVSS
AAKEFETMLW EGQHWYNRPD ISDRLFIDKS KEFLKDIVQR QVMGPVKAWF YSVEHQERGL
PHIHLCLILD FTRMEMSTED YIDEYISAEI PDLPHDGDNS HAAKLQRLFR RFILENMYHT
CSTRYCLVDG TCTKHFPRPF AEQTVIDDRI VGVQYRRRPP AQSESERLQN PERYACAVSG
RDNRFVVPHN RYLALKYRSH INVEWIQGDA CIKYVLKYVM KGCQLAFVQI VNDTSATTAG
NVVVNYDEFR QIRMARYQTP NEALLSIWGN KLVRKSHQVE HQRFHLPGQN RVVVLAGREE
ERAEEERARI AAGQEQHSAL TSYFALNAAL EPDVARGYTF MSICHDYWYD RRANQWKKRV
QRRKNHLAML EAASAGNFEH QALRMLLLHV HGPTGWHALY AGQTTFVDAA KAMGLIEDSA
LWVDTILEAL SGLPTFRRRI NWTAVLFANS GILDASSVLD RVLLDARRLL TPRAMLQQDL
DVVRQYVLCR MELVFRLHGV DPASFNSCCE RLGLPAPLGF VMPNEDIIEA EYNAGDYGNR
LWAQFLQEDS EQTDTATDGP MTTAHYAAKD AEFSPQLNDK QRAFIEAVCA SVQRRRDATL
EPAQQLFMLT GDGGTGKTFA YNALIARLKS KMACRLIATA STGIAAELLF EGATLHSKLR
VPIDIDEDTM PMLDYESDPA KLLRALELLI IDEISIANKN VISYVDKLLR SIDVAYREKH
FGGKIVVFGG DWKQLLPVAE TSGAPGLDTV NNSYWLSVKT TTWFTNGLVN IHRLTDNMRI
SGNQEDYRRT LKTWGTGVNV RTAATDDRRR PYVQLSPALC LSSEEALIDF VFGDALKDPL
ANVVQLRGAA ILCPLNKDTF KLNAELMTRI SNAVSTPVQQ SERVYISVDT VDPDSPLDVL
ALNVADRYIE NIYGKTPPGM PEHRLQLKIG AVMMVIKNIS VAHGLCNGTR VQIIALGDNI
ITCRYIQGPR ASTDFKMYRH RFRFGGRGRE ATRHGAVKWT RLQFPLRPGF VITTHKAQGQ
TLARVGVHLS SSQCFAHGQF YVAMSRVRTS DDIRVLTSAR SSNCVQNWVV QAVVDKEDIV
EARQYAGPPA AFQPPQAGPS ALLAPRSLPS EPTSNEHPDD SSDDDNDDQR PQQHRGRCQV
ASPSLPSGQQ LFPDQQPTTS VVLPPPIQQL SRRIHIDRGL YFEDVLGDGD CFYRAIVRHL
FGYDNGETVL SESDAMAQEA AQRSLRRAVA RSIQQRFHFA PEEERQRMHY FCFKFIF
//
