ID A0A183GXU1_9BILA Unreviewed; 324 AA.
AC A0A183GXU1;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Male sterility protein {ECO:0000313|WBParaSite:OFLC_0000005001-mRNA-1};
GN ORFNames=OFLC_LOCUS51 {ECO:0000313|EMBL:VDO24340.1};
OS Onchocerca flexuosa.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX NCBI_TaxID=387005 {ECO:0000313|Proteomes:UP000050787, ECO:0000313|WBParaSite:OFLC_0000005001-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:OFLC_0000005001-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDO24340.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UZAJ01000012; VDO24340.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A183GXU1; -.
DR STRING; 387005.A0A183GXU1; -.
DR WBParaSite; OFLC_0000005001-mRNA-1; OFLC_0000005001-mRNA-1; OFLC_0000005001.
DR Proteomes; UP000050787; Unplaced.
DR Proteomes; UP000267606; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0080019; F:alcohol-forming very long-chain fatty acyl-CoA reductase activity; IEA:InterPro.
DR CDD; cd09071; FAR_C; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR026055; FAR.
DR InterPro; IPR033640; FAR_C.
DR PANTHER; PTHR11011:SF45; FATTY ACYL-COA REDUCTASE; 1.
DR PANTHER; PTHR11011; MALE STERILITY PROTEIN 2-RELATED; 1.
DR Pfam; PF03015; Sterile; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 258..279
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 153..244
FT /note="Fatty acyl-CoA reductase C-terminal"
FT /evidence="ECO:0000259|Pfam:PF03015"
SQ SEQUENCE 324 AA; 38264 MW; 8EC9462270B2F055 CRC64;
MVFKTSLRNL ANQTGRHVSP RAPINVAKLD VILNFAVDMM LSPLCLQMGT DCCGKGVLTN
MCGSSSAKAD IIPVDIVSNL MIVAAAHRTY TKYESIPVIH CCSGALNPVQ WHFIVNFIER
FFRAYPLNEC YRIPSTHFHS SRFLFEFNFY MKHMGPAYLI DLLNAFWGPK IRLTRIYQKV
LRLVETLHYF TARGWDFDSK GLLELWETTS DEDKKIFNFD VRQLDWDSYL FDYLMGVKRY
VVKDRLEELP KARRNLSWLK LYATIFNAII WWISVRIFAR QRSRRYRWFS GSIGFLLTYI
WSNYNFRPPV RLKSLEEYKQ RTNF
//
