ID A0A183GZ49_9BILA Unreviewed; 917 AA.
AC A0A183GZ49;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Immunoglobulin I-set domain protein {ECO:0000313|WBParaSite:OFLC_0000050801-mRNA-1};
GN ORFNames=OFLC_LOCUS509 {ECO:0000313|EMBL:VDO26054.1};
OS Onchocerca flexuosa.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX NCBI_TaxID=387005 {ECO:0000313|Proteomes:UP000050787, ECO:0000313|WBParaSite:OFLC_0000050801-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:OFLC_0000050801-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDO26054.1, ECO:0000313|Proteomes:UP000267606}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UZAJ01000174; VDO26054.1; -; Genomic_DNA.
DR STRING; 387005.A0A183GZ49; -.
DR WBParaSite; OFLC_0000050801-mRNA-1; OFLC_0000050801-mRNA-1; OFLC_0000050801.
DR Proteomes; UP000050787; Unplaced.
DR Proteomes; UP000267606; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR CDD; cd00063; FN3; 3.
DR Gene3D; 2.60.40.10; Immunoglobulins; 4.
DR InterPro; IPR003961; FN3_dom.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR PANTHER; PTHR44170:SF39; FI24025P1; 1.
DR PANTHER; PTHR44170; PROTEIN SIDEKICK; 1.
DR Pfam; PF00041; fn3; 3.
DR Pfam; PF07679; I-set; 1.
DR SMART; SM00060; FN3; 3.
DR SMART; SM00409; IG; 1.
DR SMART; SM00408; IGc2; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 2.
DR SUPFAM; SSF48726; Immunoglobulin; 1.
DR PROSITE; PS50853; FN3; 3.
DR PROSITE; PS50835; IG_LIKE; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius}; Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|SAM:SignalP}; Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..16
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 17..917
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5041048131"
FT TRANSMEM 498..520
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 34..125
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 148..243
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 266..373
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT DOMAIN 378..472
FT /note="Fibronectin type-III"
FT /evidence="ECO:0000259|PROSITE:PS50853"
FT REGION 228..251
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 708..784
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 815..917
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 713..752
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 757..771
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 845..868
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 885..917
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 917 AA; 100948 MW; D771EF34E8A5732E CRC64;
MVFGTVLSLT TTLSLSCLYG PPYCINGTLP SHPPPIIEHG HSNQTLMIGA SAILPCAANG
RSIPQINWLK NGEQINLEDA NFETRFKQLS SGSLQIEELK KSDTGVYTCR ARNEDGESTW
SGSLVVEEHT NPSVTFTRMP NLSAFPSAPG KPSVQNITED GVDLGWAIPE RNGGTLINGY
LLQYFSPEMG QTWFNVPDYI SGPRYQLRNL KSSHSYVFIV RAENSEGIGP PSPMSDAIQT
KPQKEQSERE MTNANMDLDT ARERIASEQL IKLDEATTVN ATAVKLSWKR RRDEPLVEGY
YIKWRAVPTA SGQKQAGASG TDSHWVNISK PDIDTYIVNG LRPFKNYEFF VIPYHRTVQG
MPSNSLNGAT SEAPPTSPPT DVRVRMMNLT TLRISWRPPP ADGINGILKG FQIIVLGSGA
KYNRNITTNE RAASVTLFHL IPEMTYGVKV AARSNAGVGV YHGLEAVTMN EATLREHIQL
MSGISSGVRL LYIIKRPWFI ATAGVLIWIT FIALITFMWW RWRKSKGKAA ARLGMPFIKI
NDGSVHLTAR DALWMDHPNF NSAQRSLLNS SINGAHCNGP PIYTQTPHQA DFYMDGQILH
HDTSAHVLGT VDRAQSPNHY HYAALTAGGA STLSTFYGGH QVLDDPSPYA TTTLVMNNRQ
RWLKEHMLRA PMPPLNPVPS APPARFKENA KHHNTLGERR SPFVDSKMRS ISHHHSGSPP
HTDISYVQSS DGTGGSSNGR NKRGTLNGKR SPPKQTLLDM IPPPPPNAPP SDIQSDTHSK
ELVDSPNSQL MDVNEHYDAV SDALLFDNDG RHTHEKLSLT NTRPNSRNRI IHRSGAMGSC
GGGQEDGDSQ RSSLMNDNNR SAFCSSSEAD EENSEEDNHV GKSSSRVDRS QSPEYATHRP
SQPCMGVSAS TLTQSSC
//
