ID   A0A183H105_9BILA        Unreviewed;       266 AA.
AC   A0A183H105;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   22-FEB-2023, entry version 22.
DE   SubName: Full=SH2 domain-containing protein {ECO:0000313|WBParaSite:OFLC_0000116401-mRNA-1};
GN   ORFNames=OFLC_LOCUS1165 {ECO:0000313|EMBL:VDO28492.1};
OS   Onchocerca flexuosa.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX   NCBI_TaxID=387005 {ECO:0000313|Proteomes:UP000050787, ECO:0000313|WBParaSite:OFLC_0000116401-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:OFLC_0000116401-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO28492.1, ECO:0000313|Proteomes:UP000267606}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UZAJ01000509; VDO28492.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A183H105; -.
DR   STRING; 387005.A0A183H105; -.
DR   WBParaSite; OFLC_0000116401-mRNA-1; OFLC_0000116401-mRNA-1; OFLC_0000116401.
DR   Proteomes; UP000050787; Unplaced.
DR   Proteomes; UP000267606; Unassembled WGS sequence.
DR   Gene3D; 3.30.505.10; SH2 domain; 1.
DR   InterPro; IPR000980; SH2.
DR   InterPro; IPR036860; SH2_dom_sf.
DR   Pfam; PF00017; SH2; 1.
DR   PRINTS; PR00401; SH2DOMAIN.
DR   SMART; SM00252; SH2; 1.
DR   SUPFAM; SSF55550; SH2 domain; 1.
DR   PROSITE; PS50001; SH2; 1.
PE   4: Predicted;
KW   SH2 domain {ECO:0000256|PROSITE-ProRule:PRU00191}.
FT   DOMAIN          163..257
FT                   /note="SH2"
FT                   /evidence="ECO:0000259|PROSITE:PS50001"
FT   REGION          1..63
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        10..27
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        28..48
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        49..63
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   266 AA;  31012 MW;  71C95E55F6FC6A8E CRC64;
     MKDILGRSSF RFFRSSTTST TPSSSSNEYH HLKEEEVKDD ERQQSTSTNR RRTDPIYIPN
     SRKKNSSNDY AICEGSYDHE YMLVDIDQRL SKSAEIENRP RDVNMDQLDR VPVDFSAPSG
     PAIITDPNEI EEILMCGESR AIYQDHSKIY GLASCSMYRA ERWFHYNADQ SKVERMLLRT
     GAEDGSFLIR INERNCLVLT MCHHQKIYNI YINVKVEGHK TTFFIETLHQ FSNLIDLIKY
     YAKHQCIFLP CKLTRGVALR WPDSTK
//