ID A0A183H3N8_9BILA Unreviewed; 358 AA.
AC A0A183H3N8;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=tRNA (Cytosine(38)-C(5))-methyltransferase {ECO:0000313|WBParaSite:OFLC_0000209701-mRNA-1};
GN ORFNames=OFLC_LOCUS2098 {ECO:0000313|EMBL:VDO31866.1};
OS Onchocerca flexuosa.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX NCBI_TaxID=387005 {ECO:0000313|Proteomes:UP000050787, ECO:0000313|WBParaSite:OFLC_0000209701-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:OFLC_0000209701-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDO31866.1, ECO:0000313|Proteomes:UP000267606}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the class I-like SAM-binding methyltransferase
CC superfamily. C5-methyltransferase family. {ECO:0000256|PROSITE-
CC ProRule:PRU01016, ECO:0000256|RuleBase:RU000416}.
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DR EMBL; UZAJ01001140; VDO31866.1; -; Genomic_DNA.
DR STRING; 387005.A0A183H3N8; -.
DR WBParaSite; OFLC_0000209701-mRNA-1; OFLC_0000209701-mRNA-1; OFLC_0000209701.
DR Proteomes; UP000050787; Unplaced.
DR Proteomes; UP000267606; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR Gene3D; 3.90.120.10; DNA Methylase, subunit A, domain 2; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR001525; C5_MeTfrase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR NCBIfam; TIGR00675; dcm; 1.
DR PANTHER; PTHR46098; TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE; 1.
DR PANTHER; PTHR46098:SF1; TRNA (CYTOSINE(38)-C(5))-METHYLTRANSFERASE; 1.
DR Pfam; PF00145; DNA_methylase; 1.
DR PRINTS; PR00105; C5METTRFRASE.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS51679; SAM_MT_C5; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000256|PROSITE-
KW ProRule:PRU01016};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691,
KW ECO:0000256|PROSITE-ProRule:PRU01016};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|PROSITE-
KW ProRule:PRU01016}.
FT ACT_SITE 96
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU01016"
SQ SEQUENCE 358 AA; 41067 MW; A2E380A0FEDA0DB7 CRC64;
MFGKQQSTSF LCAKIDSNDK PMKCLEFFAG IGGFHYALKE IGLQVIIRAL DINTVTNAIY
KHNFPNTEIQ QCNIEKLRTD YYDDYNADIW TLSPPCQPFT KKGLRKDLAD RRCIALKSIC
NVLKTMKHRP RYIIVENVCG FETSEAHQML KDTLMNLCYS FEEYIISPTE IGIPNSRPRY
YLLANLTSHC ITVPATSKII EIWPTDNGTI FRRKAIGEYL CDKANEDISL AILPEKVERF
GNVMSFVIPD SLHSSCFTKS YYRYIAGTGP ILLQFSNIIQ DRELSSEQLR NFALHDNCKN
LMHCQIRYFS WREIANLLGF PRTFEKPPNI STKQMYHALG NSISVSGVAL LIQHLLKI
//
