ID A0A183H462_9BILA Unreviewed; 384 AA.
AC A0A183H462;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=GroES-like protein {ECO:0000313|WBParaSite:OFLC_0000227101-mRNA-1};
GN ORFNames=OFLC_LOCUS2274 {ECO:0000313|EMBL:VDO32455.1};
OS Onchocerca flexuosa.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX NCBI_TaxID=387005 {ECO:0000313|Proteomes:UP000050787, ECO:0000313|WBParaSite:OFLC_0000227101-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:OFLC_0000227101-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDO32455.1, ECO:0000313|Proteomes:UP000267606}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC family. Quinone oxidoreductase subfamily.
CC {ECO:0000256|ARBA:ARBA00010371}.
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DR EMBL; UZAJ01001272; VDO32455.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A183H462; -.
DR STRING; 387005.A0A183H462; -.
DR WBParaSite; OFLC_0000227101-mRNA-1; OFLC_0000227101-mRNA-1; OFLC_0000227101.
DR Proteomes; UP000050787; Unplaced.
DR Proteomes; UP000267606; Unassembled WGS sequence.
DR GO; GO:0005739; C:mitochondrion; IEA:InterPro.
DR GO; GO:0016491; F:oxidoreductase activity; IEA:InterPro.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR CDD; cd08248; RTN4I1; 1.
DR Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR InterPro; IPR013154; ADH-like_N.
DR InterPro; IPR011032; GroES-like_sf.
DR InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR InterPro; IPR020843; PKS_ER.
DR InterPro; IPR002364; Quin_OxRdtase/zeta-crystal_CS.
DR InterPro; IPR037397; RTN4I1.
DR PANTHER; PTHR11695; ALCOHOL DEHYDROGENASE RELATED; 1.
DR PANTHER; PTHR11695:SF294; RETICULON-4-INTERACTING PROTEIN 1, MITOCHONDRIAL; 1.
DR Pfam; PF08240; ADH_N; 1.
DR Pfam; PF13602; ADH_zinc_N_2; 1.
DR SMART; SM00829; PKS_ER; 1.
DR SUPFAM; SSF50129; GroES-like; 1.
DR SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
DR PROSITE; PS01162; QOR_ZETA_CRYSTAL; 1.
PE 3: Inferred from homology;
FT DOMAIN 40..379
FT /note="Enoyl reductase (ER)"
FT /evidence="ECO:0000259|SMART:SM00829"
SQ SEQUENCE 384 AA; 42373 MW; 27FF98E8E798141F CRC64;
MIVRNMQWLL GFTVASKNSL QDINSWGRRM STWVTKQFDG DMEKIEMSIP TIEKPDQLLL
KVKAASVNLI DTLMRKGYGR QLCSAVKNLR NCSLDSTTLL PFVGGRDCSG IVEQIGGNVK
KFKKGDEVIA VVDPFSSGTH AEFVVVNESN CVSKPANVSY IDGAAFPYAA CTAWSALVSI
ARINPHNAAS QRVLIHGGAG GIGTTAIQML KAWNIDKVVV TCSDDCFNMI QELGAIPVNY
KSADALEKLI SEGPFDVVLD CAQSELSEWS DRVMGLWRNS VHVSLLSPLL ADTDRYGIPL
GIASTAVKYF TKATLPIIQR GQWYSYAFFA PHPECMQQIS QFLKDGKMKP VIDQIFKYDE
LPIAYKKVLK RKGRGKTIIN MSES
//
