ID A0A183H584_9BILA Unreviewed; 441 AA.
AC A0A183H584;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=glycerol kinase {ECO:0000256|ARBA:ARBA00012099};
DE EC=2.7.1.30 {ECO:0000256|ARBA:ARBA00012099};
DE AltName: Full=ATP:glycerol 3-phosphotransferase {ECO:0000256|ARBA:ARBA00043149};
GN ORFNames=OFLC_LOCUS2645 {ECO:0000313|EMBL:VDO33718.1};
OS Onchocerca flexuosa.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX NCBI_TaxID=387005 {ECO:0000313|Proteomes:UP000050787, ECO:0000313|WBParaSite:OFLC_0000264301-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:OFLC_0000264301-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDO33718.1, ECO:0000313|Proteomes:UP000267606}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol kinase
CC pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
CC {ECO:0000256|ARBA:ARBA00005190}.
CC -!- SIMILARITY: Belongs to the FGGY kinase family.
CC {ECO:0000256|ARBA:ARBA00009156, ECO:0000256|RuleBase:RU003733}.
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DR EMBL; UZAJ01001558; VDO33718.1; -; Genomic_DNA.
DR STRING; 387005.A0A183H584; -.
DR WBParaSite; OFLC_0000264301-mRNA-1; OFLC_0000264301-mRNA-1; OFLC_0000264301.
DR UniPathway; UPA00618; UER00672.
DR Proteomes; UP000050787; Unplaced.
DR Proteomes; UP000267606; Unassembled WGS sequence.
DR GO; GO:0004370; F:glycerol kinase activity; IEA:UniProtKB-EC.
DR GO; GO:0019563; P:glycerol catabolic process; IEA:UniProtKB-UniPathway.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.30.420.40; -; 3.
DR InterPro; IPR043129; ATPase_NBD.
DR InterPro; IPR000577; Carb_kinase_FGGY.
DR InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR InterPro; IPR018485; FGGY_C.
DR InterPro; IPR018484; FGGY_N.
DR PANTHER; PTHR10196:SF69; GLYCEROL KINASE; 1.
DR PANTHER; PTHR10196; SUGAR KINASE; 1.
DR Pfam; PF02782; FGGY_C; 1.
DR Pfam; PF00370; FGGY_N; 1.
DR PIRSF; PIRSF000538; GlpK; 2.
DR SUPFAM; SSF53067; Actin-like ATPase domain; 2.
DR PROSITE; PS00933; FGGY_KINASES_1; 1.
DR PROSITE; PS00445; FGGY_KINASES_2; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000256|RuleBase:RU003733};
KW Transferase {ECO:0000256|RuleBase:RU003733}.
FT DOMAIN 8..257
FT /note="Carbohydrate kinase FGGY N-terminal"
FT /evidence="ECO:0000259|Pfam:PF00370"
FT DOMAIN 305..426
FT /note="Carbohydrate kinase FGGY C-terminal"
FT /evidence="ECO:0000259|Pfam:PF02782"
SQ SEQUENCE 441 AA; 48478 MW; BAA2D820F8A11A94 CRC64;
MDFKNKLIGA IDQSTSSTRL IIYQLNPRKI IASHQIELRQ IFPRAGWVEI DPAEIFAATL
KCIIECCDSI KVTGYDITDI KAIGICNQRE TTILWDGKSG KPLYNAICWL DDRTTDLVHS
FIEKTSNKSE NQFKEITGLP IFSYFSALKI RWLLNNVDNV KDALKRGTLM FGTVDSWLIY
KFTGRHITDV TNASRTLLMS IKTLNWSEEL CNFFGIPMNI LPEIHSSAEI YALMNIGPLK
GVPISGCLGD QQAAMFGECC FNPGETKCTY GTGTFMLANI GDDPVISGNG LLTTVAYQDA
CEIETAAASV SGSGGVVFVP CFTGLYTPYW DSSARGIICG LVQTTKREHI IRAVIEAVCF
QTVEMVEAIR TDVSHNKEIK ILKVDGGLTK SSLFLQLLSD ILGIDVIKAS NIEASSWGAA
VVAAIGAKII RFNYNRLSSK G
//
