ID   A0A183HAN2_9BILA        Unreviewed;       374 AA.
AC   A0A183HAN2;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   22-FEB-2023, entry version 19.
DE   SubName: Full=CTP_synth_N domain-containing protein {ECO:0000313|WBParaSite:OFLC_0000454301-mRNA-1};
GN   ORFNames=OFLC_LOCUS4544 {ECO:0000313|EMBL:VDO40281.1};
OS   Onchocerca flexuosa.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX   NCBI_TaxID=387005 {ECO:0000313|Proteomes:UP000050787, ECO:0000313|WBParaSite:OFLC_0000454301-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:OFLC_0000454301-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO40281.1, ECO:0000313|Proteomes:UP000267606}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UZAJ01003493; VDO40281.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A183HAN2; -.
DR   STRING; 387005.A0A183HAN2; -.
DR   WBParaSite; OFLC_0000454301-mRNA-1; OFLC_0000454301-mRNA-1; OFLC_0000454301.
DR   Proteomes; UP000050787; Unplaced.
DR   Proteomes; UP000267606; Unassembled WGS sequence.
DR   GO; GO:0003883; F:CTP synthase activity; IEA:InterPro.
DR   GO; GO:0006541; P:glutamine metabolic process; IEA:UniProtKB-KW.
DR   GO; GO:0006221; P:pyrimidine nucleotide biosynthetic process; IEA:InterPro.
DR   CDD; cd03113; CTPS_N; 1.
DR   Gene3D; 3.40.50.880; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR029062; Class_I_gatase-like.
DR   InterPro; IPR004468; CTP_synthase.
DR   InterPro; IPR017456; CTP_synthase_N.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR11550; CTP SYNTHASE; 1.
DR   PANTHER; PTHR11550:SF0; CTP SYNTHASE-RELATED; 1.
DR   Pfam; PF06418; CTP_synth_N; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
PE   4: Predicted;
KW   Glutamine amidotransferase {ECO:0000256|ARBA:ARBA00022962}.
FT   DOMAIN          6..276
FT                   /note="CTP synthase N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF06418"
SQ   SEQUENCE   374 AA;  42069 MW;  92E9D35EDD750860 CRC64;
     MVEPVKMILV TGGVISGVGK GIISSSLGVL LKAHGYRVSF IKIDPYINID AGTFSPFEHG
     EVFVLDDGGE VDLDLGNYER FLNIRLTRDN NITTGKIYQQ VIERERRGDY LGKTVQTIPH
     ITNAIIEWVE RVAAIPVDGK NQRPEVCIVE LGGTIGDIES MPFVAAFEKF QRPKFKDHLM
     TVHVSVILEP KSTGELKTKP MQNSMRNLRA SGLTPDLLVC RSERPLNKAL REKIAAFGMV
     ELEQVIGVHD VSNIYKVPLL LHKQNVLEMV VKRLKLTAVN AEGTLTQKPN LFQWTHLSNL
     CDSFQEEVRI ALVGKYVQIP DAYASLNKAL RHSAIHAKRQ LVISYICSEH LEETNDSERI
     SDYNHAWEMI KQCQ
//