ID   A0A183HAR5_9BILA        Unreviewed;       370 AA.
AC   A0A183HAR5;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=E1-E2 ATPase {ECO:0000313|WBParaSite:OFLC_0000457601-mRNA-1};
GN   ORFNames=OFLC_LOCUS4578 {ECO:0000313|EMBL:VDO40388.1};
OS   Onchocerca flexuosa.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX   NCBI_TaxID=387005 {ECO:0000313|Proteomes:UP000050787, ECO:0000313|WBParaSite:OFLC_0000457601-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:OFLC_0000457601-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO40388.1, ECO:0000313|Proteomes:UP000267606}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UZAJ01003539; VDO40388.1; -; Genomic_DNA.
DR   STRING; 387005.A0A183HAR5; -.
DR   WBParaSite; OFLC_0000457601-mRNA-1; OFLC_0000457601-mRNA-1; OFLC_0000457601.
DR   Proteomes; UP000050787; Unplaced.
DR   Proteomes; UP000267606; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   Gene3D; 3.40.1110.10; Calcium-transporting ATPase, cytoplasmic domain N; 1.
DR   Gene3D; 2.70.150.10; Calcium-transporting ATPase, cytoplasmic transduction domain A; 1.
DR   Gene3D; 1.20.1110.10; Calcium-transporting ATPase, transmembrane domain; 1.
DR   Gene3D; 3.40.50.1000; HAD superfamily/HAD-like; 1.
DR   InterPro; IPR023299; ATPase_P-typ_cyto_dom_N.
DR   InterPro; IPR018303; ATPase_P-typ_P_site.
DR   InterPro; IPR023298; ATPase_P-typ_TM_dom_sf.
DR   InterPro; IPR008250; ATPase_P-typ_transduc_dom_A_sf.
DR   InterPro; IPR023214; HAD_sf.
DR   InterPro; IPR001757; P_typ_ATPase.
DR   NCBIfam; TIGR01494; ATPase_P-type; 1.
DR   PANTHER; PTHR43294:SF4; CATION TRANSPORTING ATPASE; 1.
DR   PANTHER; PTHR43294; SODIUM/POTASSIUM-TRANSPORTING ATPASE SUBUNIT ALPHA; 1.
DR   Pfam; PF00122; E1-E2_ATPase; 1.
DR   PRINTS; PR00121; NAKATPASE.
DR   SUPFAM; SSF81653; Calcium ATPase, transduction domain A; 1.
DR   SUPFAM; SSF81665; Calcium ATPase, transmembrane domain M; 1.
DR   PROSITE; PS00154; ATPASE_E1_E2; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        19..40
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        184..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        218..243
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   370 AA;  41230 MW;  9D7D08D1837889C4 CRC64;
     MLSLATYIIH LIHGNNEPVN LYCALILISI VILMCFVAFY QEKQTLQVIN DLKSVLPTSC
     IVIRDSKTQQ VPEEELVTGD LVVITAGAII PADIRILQSN GLKIETSAVT GDKEAYDYTH
     EAVATYLSIF EARNVAFKGS FCLEGDGIGI VIRTGKYTVL GYIINIHQQV SKTRSKLKME
     IDEFVNFISV VALVMAIVFF LFGSFINNFK NVLDHFIIGF LIIIVANVPQ GLPAMVISQL
     AIIGRRLASK NVYIKKLDII DELGATTVVA TDKTGTLTKN SMVLTDLWYN RKHHPNHNYV
     NNQSVLNMNC PKPIIEQPLS DMFVVMSVCN RAHFECARKS KHSTSEKEAQ KKSSGKMLNM
     GQVSKRFIVL
//