ID   A0A183HH84_9BILA        Unreviewed;       245 AA.
AC   A0A183HH84;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Neur_chan_memb domain-containing protein {ECO:0000313|WBParaSite:OFLC_0000684501-mRNA-1};
OS   Onchocerca flexuosa.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX   NCBI_TaxID=387005 {ECO:0000313|Proteomes:UP000050787, ECO:0000313|WBParaSite:OFLC_0000684501-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:OFLC_0000684501-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
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DR   AlphaFoldDB; A0A183HH84; -.
DR   STRING; 387005.A0A183HH84; -.
DR   WBParaSite; OFLC_0000684501-mRNA-1; OFLC_0000684501-mRNA-1; OFLC_0000684501.
DR   Proteomes; UP000050787; Unplaced.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005230; F:extracellular ligand-gated monoatomic ion channel activity; IEA:UniProt.
DR   GO; GO:0004888; F:transmembrane signaling receptor activity; IEA:InterPro.
DR   CDD; cd19049; LGIC_TM_anion; 1.
DR   Gene3D; 1.20.58.390; Neurotransmitter-gated ion-channel transmembrane domain; 1.
DR   InterPro; IPR006028; GABAA/Glycine_rcpt.
DR   InterPro; IPR006201; Neur_channel.
DR   InterPro; IPR036719; Neuro-gated_channel_TM_sf.
DR   InterPro; IPR038050; Neuro_actylchol_rec.
DR   InterPro; IPR006029; Neurotrans-gated_channel_TM.
DR   PANTHER; PTHR18945:SF835; GAMMA-AMINOBUTYRIC ACID RECEPTOR ALPHA-LIKE; 1.
DR   PANTHER; PTHR18945; NEUROTRANSMITTER GATED ION CHANNEL; 1.
DR   Pfam; PF02932; Neur_chan_memb; 1.
DR   PRINTS; PR00253; GABAARECEPTR.
DR   SUPFAM; SSF90112; Neurotransmitter-gated ion-channel transmembrane pore; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        62..85
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        126..147
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          68..162
FT                   /note="Neurotransmitter-gated ion-channel transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF02932"
SQ   SEQUENCE   245 AA;  28220 MW;  791B8662DAB94122 CRC64;
     LKDFNCKTAV KVEPFELTSF RFTNLCTNKT IATTSSELIN YKIGSGSYSR LRAQFLFERQ
     SSFYMIQIYI PAILVVFISW VSFWINPESA PSRTVIGTLT ILSETHLLMS TNRRLPPVSY
     IKAVDIYLGF CYLNVIMALV EYATVAYSKK KYEDEEKHKS KNIFELKLHT PDLLRDARID
     ECTCKQEIFL VPKKSSKCTN CFTHSRVDLI ARIVFPISVC YHFILASPAS HHFCKILLPP
     KFDNL
//