ID A0A183HY06_9BILA Unreviewed; 435 AA.
AC A0A183HY06;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE SubName: Full=Ammonium_transp domain-containing protein {ECO:0000313|WBParaSite:OFLC_0001236901-mRNA-1};
GN ORFNames=OFLC_LOCUS12368 {ECO:0000313|EMBL:VDP11171.1};
OS Onchocerca flexuosa.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX NCBI_TaxID=387005 {ECO:0000313|Proteomes:UP000050787, ECO:0000313|WBParaSite:OFLC_0001236901-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:OFLC_0001236901-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDP11171.1, ECO:0000313|Proteomes:UP000267606}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the ammonium transporter (TC 2.A.49) family. Rh
CC subfamily. {ECO:0000256|ARBA:ARBA00011036}.
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DR EMBL; UZAJ01039831; VDP11171.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A183HY06; -.
DR STRING; 387005.A0A183HY06; -.
DR WBParaSite; OFLC_0001236901-mRNA-1; OFLC_0001236901-mRNA-1; OFLC_0001236901.
DR Proteomes; UP000050787; Unplaced.
DR Proteomes; UP000267606; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:InterPro.
DR GO; GO:0008519; F:ammonium transmembrane transporter activity; IEA:InterPro.
DR Gene3D; 1.10.3430.10; Ammonium transporter AmtB like domains; 1.
DR InterPro; IPR029020; Ammonium/urea_transptr.
DR InterPro; IPR024041; NH4_transpt_AmtB-like_dom.
DR InterPro; IPR002229; RhesusRHD.
DR PANTHER; PTHR11730; AMMONIUM TRANSPORTER; 1.
DR PANTHER; PTHR11730:SF60; RH50, ISOFORM D; 1.
DR Pfam; PF00909; Ammonium_transp; 1.
DR PRINTS; PR00342; RHESUSRHD.
DR SUPFAM; SSF111352; Ammonium transporter; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 17..36
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 48..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 77..101
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 169..188
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 208..227
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..258
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 264..282
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 303..320
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 354..375
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 5..378
FT /note="Ammonium transporter AmtB-like"
FT /evidence="ECO:0000259|Pfam:PF00909"
SQ SEQUENCE 435 AA; 47591 MW; EE4BFBB079E8CCB2 CRC64;
MPGGTTSTNF INTNYPLFQD VHLMTLVGMG FIMVFLRRYG LAALSINLLL TSHAIQWALI
VRGFFSHEFA NVGRFSISIL DLITADFVAI TVLITMGAVL GKLTPVQYMV MSAIEVPVAV
AVEHLILRYL KVIDIGRSMV IHCFGAYFGL AVAKVINKRE MIAHQHEGSS YNSNIFAMIG
TLFLWAFFPS FNSALAIPED SRHRAILNSY LALCSSTVCT FLISQMLDHE NKYRFSMTHI
SNSVLAGGIA IGTVANIILE PFYALLIGCL GALVSVLGNN YIRPIGARVF GLHDTRGVGS
IHGLPGILAG ILGFVFTAVY EPTRYGTGNV THIYPAMSNS KEGREIFVQA GYQLAALVIV
LLVSIIGGAV TGLILRLNCF NRIHDKEFYS DGEFIEPPED YDFTTRIISK IDHIELTEHT
ALNKESSSSV GPSNP
//
