ID   A0A183HZU1_9BILA        Unreviewed;      1301 AA.
AC   A0A183HZU1;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   24-JAN-2024, entry version 27.
DE   SubName: Full=FANCI_HD2 domain-containing protein {ECO:0000313|WBParaSite:OFLC_0001300401-mRNA-1};
GN   ORFNames=OFLC_LOCUS13003 {ECO:0000313|EMBL:VDP12691.1};
OS   Onchocerca flexuosa.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX   NCBI_TaxID=387005 {ECO:0000313|Proteomes:UP000050787, ECO:0000313|WBParaSite:OFLC_0001300401-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:OFLC_0001300401-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDP12691.1, ECO:0000313|Proteomes:UP000267606}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UZAJ01040006; VDP12691.1; -; Genomic_DNA.
DR   STRING; 387005.A0A183HZU1; -.
DR   WBParaSite; OFLC_0001300401-mRNA-1; OFLC_0001300401-mRNA-1; OFLC_0001300401.
DR   Proteomes; UP000050787; Unplaced.
DR   Proteomes; UP000267606; Unassembled WGS sequence.
DR   GO; GO:0006281; P:DNA repair; IEA:InterPro.
DR   InterPro; IPR026171; FANCI.
DR   InterPro; IPR029312; FANCI_HD2.
DR   PANTHER; PTHR21818; BC025462 PROTEIN; 1.
DR   PANTHER; PTHR21818:SF0; FANCONI ANEMIA GROUP I PROTEIN; 1.
DR   Pfam; PF14680; FANCI_HD2; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils}.
FT   DOMAIN          552..772
FT                   /note="FANCI helical"
FT                   /evidence="ECO:0000259|Pfam:PF14680"
FT   REGION          1268..1301
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          750..784
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        1285..1301
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1301 AA;  148050 MW;  EAED6F44176CFA70 CRC64;
     MDTTDMTCPT QSSQHVRTHE SFCTQFCAQV DKYVMSGCPQ NNEKYVQQIT KILSQLSEER
     RWQNFTNFVK QQCEKDGGKL FSNFVKSWYI AIGHVNAKTD YILPMLLLVM EMMKTDNFEY
     EPVIMLHSIL EEEIRKMNGR DTKLFGTYLA ENFISGWLLR KRWLSATTLF LQCLVKSEDK
     FIEWQENTIN CVEYRVVFLL KLLNDVVSCN SFKELIIVLR KCSLYEILGL FVEQMLQTEA
     TPEICLKLII VLPEICDHLL AKTDFPFEDL YALSIELHEL FESSVTVPKL FLARLKRHRQ
     LVSCNKFALI CLLSLCNTTR YHSVSMAELK QNIVKLQKHC NQLKRSAWIR DVMGNCDVET
     LKGNLDAVVE AAVSDVKWCS VIGSALEQVA FILLLDKCNT EVKFSDGRIV DDASAISLGK
     SILVSLAKVD VTSIGQLLER ILTILFTCVK QNSAFILIDT IVDIVSKQTV HVLNAWKSLQ
     TWMDSICDLK ETVAVSLVRA LLPVIILRPQ LLSIILNRMK KHLLCDSTVA TVLPILLLFL
     RSSTMRSAVK SDYYSQSFAT FSTQALQNMG VETKNTNVEL SLEIIGILKR TFSQPASVKS
     MLGIIEAASA NQNLVYPTLD LLVTHLATLQ QISRNTYIES SKSSTILLEP LSDLIQTISL
     LMRLSIYNLR NTSTQVVSGE DAKVCQAMSE LDKLIEFAID RDVHDLQLDK LSDFSFSVAG
     RTNLSFASLM ISLYDALIEH LWNVGSVLIR REAAEKLLAL LRRREELNEV LKEKSAKRKE
     SKGEKVIVTY SSTVPYLQSI TSIVSRFIQK VDDGDIDINE ECLQLLRENA FVWTMDWAQR
     ISIDIYKCKT RASFITLSSF SSTMLLLYIG GNFVHETASF ELWDHKCTQA IMALSNVISL
     MISKYGFRCD GFLMEMWHIL DKSNDDQRKH ENAASLMIRY ILSHLIPKLL ETYKDFEERK
     MASDFTHQAC ALITICRILF QQVSNEKAQL QCAKLIRSIL QKNEIGDRTV LKEVWHLYMH
     IERAGSYGTH YTNFLRTAAT QIITILNNKE KETVHLLTSI NDVTVETSAE MVAAACSSSL
     SDARLTTEMM SQIFISSIDT GLVKVIDLCS RLAHVVLLLL SIYVDYAVVK EPICALLTAQ
     YEALNTIVKL MLKTHKYSDI SEWAAVTKLA TLAHGSVLRI MENADENVGT LNPFDEPSLT
     HNRKVVKSQK DETLYVTYVR SRELYQANLL LLCSALHDDR LDIQVRNNSI GVRDFRIDVE
     KLRQRMEELG EEAESQGQIQ NDQQKPVKKR ARIEKENAEN A
//