ID A0A183I0D3_9BILA Unreviewed; 619 AA.
AC A0A183I0D3;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=RUN domain-containing protein {ECO:0000313|WBParaSite:OFLC_0001319601-mRNA-1};
GN ORFNames=OFLC_LOCUS13195 {ECO:0000313|EMBL:VDP13144.1};
OS Onchocerca flexuosa.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Spirurina; Spiruromorpha; Filarioidea; Onchocercidae; Onchocerca.
OX NCBI_TaxID=387005 {ECO:0000313|Proteomes:UP000050787, ECO:0000313|WBParaSite:OFLC_0001319601-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:OFLC_0001319601-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDP13144.1, ECO:0000313|Proteomes:UP000267606}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UZAJ01040084; VDP13144.1; -; Genomic_DNA.
DR STRING; 387005.A0A183I0D3; -.
DR WBParaSite; OFLC_0001319601-mRNA-1; OFLC_0001319601-mRNA-1; OFLC_0001319601.
DR Proteomes; UP000050787; Unplaced.
DR Proteomes; UP000267606; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15721; FYVE_RUFY1_like; 1.
DR CDD; cd17681; RUN_RUFY1_like; 1.
DR Gene3D; 1.20.58.900; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR047335; RUFY1-3.
DR InterPro; IPR004012; Run_dom.
DR InterPro; IPR037213; Run_dom_sf.
DR InterPro; IPR000306; Znf_FYVE.
DR InterPro; IPR017455; Znf_FYVE-rel.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR45956; RUN AND FYVE DOMAIN-CONTAINING PROTEIN 2-LIKE PROTEIN; 1.
DR PANTHER; PTHR45956:SF6; RUN DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01363; FYVE; 1.
DR Pfam; PF02759; RUN; 1.
DR SMART; SM00064; FYVE; 1.
DR SMART; SM00593; RUN; 1.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR SUPFAM; SSF140741; RUN domain-like; 1.
DR PROSITE; PS50826; RUN; 1.
DR PROSITE; PS50178; ZF_FYVE; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00091}.
FT DOMAIN 90..242
FT /note="RUN"
FT /evidence="ECO:0000259|PROSITE:PS50826"
FT DOMAIN 545..603
FT /note="FYVE-type"
FT /evidence="ECO:0000259|PROSITE:PS50178"
FT COILED 338..533
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 619 AA; 71770 MW; A31092ADC11A7C0B CRC64;
MRYWKYSTYW SILFPGRNIV NGTNSLVLLP CNLSTTMNVL ELFGFDFSTT LSETQKLTKD
YERSNLLFIT RLVLRVFLDE SMRSRHRIID VEIRSLTDLF VMLEKVLWHV QKTMIALRTP
DSELWSCLGK VANINTDMNE SYQCIDRLDK ITTPLLRIRA FLRLAVMQKK LGNYFENLYC
IHSEDKFENI LVYLINFKTD DENVFRDFYE PWALIRHDEC IGLSGALMAL SVLDCNLVLD
QAELEKQPVT VELAAYVHLP NISIHSNSEK ESDLVNARSL ELALDQKNYL EQRNHYLESK
VVELKTKMEE ISLSTLNNLT DATTEDVSTV TNEHIVTMEA LEKEKAELAQ LASEKEDSIQ
ILRQQLADTK KVNVDLYEKI RVVEGKYRQL EKDMMSANKR YNHEREQQQQ IISVLNERNS
VREMDLEHET GTSEMLKKEL ADKTDEYMQT LNVLEKKQQE LAVANDRLGK LQRQTSELNE
KLKQLPVIKQ ELEELTASYK YKSEKLEECE KALEELGGHL SESKLKVVEL KEELLPLSEA
EWEKDGSVLN CKGCNLQFSM SKRKHHCRNC GSIFCNSCTD ARVKLPSSAK PVRVCLHCYN
LLRSRHNSSL EENSSLNSF
//
