ID A0A183IDX4_9BILA Unreviewed; 406 AA.
AC A0A183IDX4;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=CEGF domain-containing protein {ECO:0000313|WBParaSite:SBAD_0000190601-mRNA-1};
GN ORFNames=SBAD_LOCUS1818 {ECO:0000313|EMBL:VDO95583.1};
OS Soboliphyme baturini.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Dioctophymatida; Dioctophymatoidea; Soboliphymatidae; Soboliphyme.
OX NCBI_TaxID=241478 {ECO:0000313|Proteomes:UP000050793, ECO:0000313|WBParaSite:SBAD_0000190601-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:SBAD_0000190601-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDO95583.1, ECO:0000313|Proteomes:UP000270296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
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DR EMBL; UZAM01006965; VDO95583.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A183IDX4; -.
DR WBParaSite; SBAD_0000190601-mRNA-1; SBAD_0000190601-mRNA-1; SBAD_0000190601.
DR Proteomes; UP000050793; Unplaced.
DR Proteomes; UP000270296; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR GO; GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
DR CDD; cd00112; LDLa; 3.
DR Gene3D; 2.10.25.10; Laminin; 1.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 3.
DR Gene3D; 2.120.10.30; TolB, C-terminal domain; 1.
DR InterPro; IPR011042; 6-blade_b-propeller_TolB-like.
DR InterPro; IPR026823; cEGF.
DR InterPro; IPR018097; EGF_Ca-bd_CS.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR000033; LDLR_classB_rpt.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR PANTHER; PTHR22722; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED PROTEIN 2-RELATED; 1.
DR PANTHER; PTHR22722:SF14; MEGALIN, ISOFORM A; 1.
DR Pfam; PF12662; cEGF; 1.
DR Pfam; PF00057; Ldl_recept_a; 3.
DR PRINTS; PR00261; LDLRECEPTOR.
DR SMART; SM00192; LDLa; 3.
DR SMART; SM00135; LY; 3.
DR SUPFAM; SSF57196; EGF/Laminin; 1.
DR SUPFAM; SSF57424; LDL receptor-like module; 3.
DR SUPFAM; SSF63825; YWTD domain; 1.
DR PROSITE; PS01187; EGF_CA; 1.
DR PROSITE; PS01209; LDLRA_1; 2.
DR PROSITE; PS50068; LDLRA_2; 3.
DR PROSITE; PS51120; LDLRB; 1.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; EGF-like domain {ECO:0000256|ARBA:ARBA00022536};
KW Endocytosis {ECO:0000256|ARBA:ARBA00022583};
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Receptor {ECO:0000256|ARBA:ARBA00023170};
KW Reference proteome {ECO:0000313|Proteomes:UP000270296};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729}.
FT DOMAIN 141..163
FT /note="Complement Clr-like EGF"
FT /evidence="ECO:0000259|Pfam:PF12662"
FT REPEAT 298..340
FT /note="LDL-receptor class B"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00461"
FT DISULFID 45..57
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 52..70
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 64..79
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 104..119
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
SQ SEQUENCE 406 AA; 46769 MW; 30EE183E712B584B CRC64;
MVSCYLYQFR CKDGSQCIQK SWKCDGSKDC RDGSDEPDDC EFPECGPGYF QCKNKRCQPV
KFRCDYYDDC GDNSDEENCG AYRCPLNQWN CPHSGHCIDT EKLCDGKDDC SDRADELNCS
RILCGALSCD FVCRSSPDGG VCACPQGYRV NQTDRRSCQD INECSEYGYC DQLCENHRPG
FRCMCFSDCY ELILKNDRGY CRSHEYNRMR LLVARREGLY RINPFDDRQP SEKLLSGKFL
YGVNYDFETH KLFWVERDAS EIYEGNFDEE FNGIINYRKL PLSGLVRPRN IAVDWITKKL
YIVEAGSNRI DISDFSGQHR TVLIMDDMTL PVDIAVDPTR GLMFFTNEKK LERSGMDGSD
RQVLVANHTY QITSVTLDLV GARVYWCDPK IDVLESVKYD GTGRYL
//
