ID   A0A183IJA5_9BILA        Unreviewed;       798 AA.
AC   A0A183IJA5;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=CULLIN_2 domain-containing protein {ECO:0000313|WBParaSite:SBAD_0000386901-mRNA-1};
GN   ORFNames=SBAD_LOCUS3701 {ECO:0000313|EMBL:VDP02089.1};
OS   Soboliphyme baturini.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC   Dioctophymatida; Dioctophymatoidea; Soboliphymatidae; Soboliphyme.
OX   NCBI_TaxID=241478 {ECO:0000313|Proteomes:UP000050793, ECO:0000313|WBParaSite:SBAD_0000386901-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SBAD_0000386901-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDP02089.1, ECO:0000313|Proteomes:UP000270296}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC       {ECO:0000256|ARBA:ARBA00004906}.
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
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DR   EMBL; UZAM01007901; VDP02089.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A183IJA5; -.
DR   WBParaSite; SBAD_0000386901-mRNA-1; SBAD_0000386901-mRNA-1; SBAD_0000386901.
DR   Proteomes; UP000050793; Unplaced.
DR   Proteomes; UP000270296; Unassembled WGS sequence.
DR   GO; GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 4.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016157; Cullin_CS.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR019559; Cullin_neddylation_domain.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF168; CULLIN-3; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   Pfam; PF10557; Cullin_Nedd8; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SMART; SM00884; Cullin_Nedd8; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS01256; CULLIN_1; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000270296};
KW   Ubl conjugation {ECO:0000256|ARBA:ARBA00022843}.
FT   DOMAIN          381..644
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
SQ   SEQUENCE   798 AA;  92909 MW;  9217170C871C86A1 CRC64;
     MKPAKKEGMN KMRIRAFPMT MDEKYVQSTW ELLRNAVQEI QKKNNSGLSF EELYRNAYTM
     VLHKHGDKLY SGLKEVVIEH LCNKVRTDVL NAMNNNFLEV LINAWIDHTT SMVMIRDILM
     YMDRVYVQQH NVVPVYNLGL ILFRDEVIRY DGIREFLRNK LLDMIMAERR GEVVQMIGIK
     NACQMLMALG IDSRTVYEED FENPFLQQSA EFYKAESQKF LGENSASVYI KKVEQRIHEE
     SERAKHYLDL STEAKIVQVL ERELISRNMK VIVEMENSGV VHMLKNDRYD SLKCMYRLLK
     RVNDGLKTMT ECTSAYLREQ GKALVQDLDG DMARSPVQYI QGLLDLKDRF NRFLMEAFEN
     EKMFKQVIAT DFEYFLNLNP KSPEYLSLFI DDKLKKGVKG MNESEVEAVL DKSMVLFRYL
     QEKDVFERYY KQHLAKRLLL NRSLSDDAEK NMISKLKFTS KLEGMFKDIQ VSATLMESYK
     QQKEYVDHCP NSGVDIFVRV LTTGFWPTQS SLPICILPRT VNDAFEKFKK YYLSKHSGRK
     VTLQPQLGSA DLHATFYGSR NSLSFVSSTS AADIDDAEQP SSSGINEGSL EKFGYPRKHI
     LCVSTYQMCV LMLFNKRERY SYEEIASETV IPEKDLKRAI QSLAMGKASQ RILCRRSPDK
     SKEIAALHHM VVLESIRKLF YDSLGNYDLF SVNDSFTSRL YRVKIQTVSA KGESEPERVE
     TRNKVDEDRK HEIEAAVVRV MKARKCLQHN MLIAEVTNQL KHRFMPSPVA IKKRIESLIE
     REYLSRDQGD HKLYHYVA
//