ID A0A183J4D9_9BILA Unreviewed; 251 AA.
AC A0A183J4D9;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 22-FEB-2023, entry version 17.
DE RecName: Full=SPRY domain-containing SOCS box protein 3 {ECO:0000256|ARBA:ARBA00014684};
GN ORFNames=SBAD_LOCUS10737 {ECO:0000313|EMBL:VDP34254.1};
OS Soboliphyme baturini.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Enoplea; Dorylaimia;
OC Dioctophymatida; Dioctophymatoidea; Soboliphymatidae; Soboliphyme.
OX NCBI_TaxID=241478 {ECO:0000313|Proteomes:UP000050793, ECO:0000313|WBParaSite:SBAD_0001111301-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:SBAD_0001111301-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDP34254.1, ECO:0000313|Proteomes:UP000270296}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May be a substrate recognition component of a SCF-like ECS
CC (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase
CC complex which mediates the ubiquitination and subsequent proteasomal
CC degradation of target proteins. {ECO:0000256|ARBA:ARBA00004094}.
CC -!- SIMILARITY: Belongs to the SPSB family.
CC {ECO:0000256|ARBA:ARBA00010910}.
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DR EMBL; UZAM01014492; VDP34254.1; -; Genomic_DNA.
DR WBParaSite; SBAD_0001111301-mRNA-1; SBAD_0001111301-mRNA-1; SBAD_0001111301.
DR Proteomes; UP000050793; Unplaced.
DR Proteomes; UP000270296; Unassembled WGS sequence.
DR CDD; cd12876; SPRY_SOCS3; 1.
DR Gene3D; 2.60.120.920; -; 1.
DR InterPro; IPR001870; B30.2/SPRY.
DR InterPro; IPR043136; B30.2/SPRY_sf.
DR InterPro; IPR013320; ConA-like_dom_sf.
DR InterPro; IPR001496; SOCS_box.
DR InterPro; IPR003877; SPRY_dom.
DR InterPro; IPR035754; SPRY_SPSB3.
DR PANTHER; PTHR12245; SPRY DOMAIN CONTAINING SOCS BOX PROTEIN; 1.
DR PANTHER; PTHR12245:SF12; SPRY DOMAIN-CONTAINING SOCS BOX PROTEIN 3; 1.
DR Pfam; PF00622; SPRY; 1.
DR SMART; SM00449; SPRY; 1.
DR SUPFAM; SSF49899; Concanavalin A-like lectins/glucanases; 1.
DR PROSITE; PS50188; B302_SPRY; 1.
DR PROSITE; PS50225; SOCS; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000270296}.
FT DOMAIN 1..208
FT /note="B30.2/SPRY"
FT /evidence="ECO:0000259|PROSITE:PS50188"
FT DOMAIN 198..248
FT /note="SOCS box"
FT /evidence="ECO:0000259|PROSITE:PS50225"
SQ SEQUENCE 251 AA; 28820 MW; 29B0800B957DB687 CRC64;
MPTNGKDVHC HQALALATMY SPQNCFDENW HWNKHDRGPD VYVYNSGRSC MFHPGWSNGT
SAIRGTMPLK DGIHYWETDV SHRIFGTSVM FGVGTRRASL HRNGFTNLLG MDGQSWGLSH
KGLLWHDGMS VAYVEPFLEN TPTTIGMLVD TPRAIVSYFK DGRXXXXXXX XXXXXFTGLD
FVREDLYPMI SSSASRTQMT LSVTRRSFDS LQDRCCWQIV RRLRTPRDVD KLLVPCRIQE
YLRTRTTWVL R
//
