ID A0A183JDT2_9TREM Unreviewed; 467 AA.
AC A0A183JDT2;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=IRF tryptophan pentad repeat domain-containing protein {ECO:0000313|WBParaSite:SCUD_0000084401-mRNA-1};
GN ORFNames=SCUD_LOCUS845 {ECO:0000313|EMBL:VDO64142.1};
OS Schistosoma curassoni.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6186 {ECO:0000313|Proteomes:UP000050789, ECO:0000313|WBParaSite:SCUD_0000084401-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:SCUD_0000084401-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDO64142.1, ECO:0000313|Proteomes:UP000279833}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Dakar {ECO:0000313|EMBL:VDO64142.1}, and Dakar, Senegal
RC {ECO:0000313|Proteomes:UP000279833};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; UZAK01000622; VDO64142.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A183JDT2; -.
DR STRING; 6186.A0A183JDT2; -.
DR WBParaSite; SCUD_0000084401-mRNA-1; SCUD_0000084401-mRNA-1; SCUD_0000084401.
DR Proteomes; UP000050789; Unplaced.
DR Proteomes; UP000279833; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IEA:InterPro.
DR GO; GO:0045893; P:positive regulation of DNA-templated transcription; IEA:UniProt.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:UniProt.
DR CDD; cd00103; IRF; 1.
DR Gene3D; 2.60.200.10; -; 1.
DR Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR InterPro; IPR019817; Interferon_reg_fac_CS.
DR InterPro; IPR001346; Interferon_reg_fact_DNA-bd_dom.
DR InterPro; IPR019471; Interferon_reg_factor-3.
DR InterPro; IPR017855; SMAD-like_dom_sf.
DR InterPro; IPR008984; SMAD_FHA_dom_sf.
DR InterPro; IPR036388; WH-like_DNA-bd_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11949; INTERFERON REGULATORY FACTOR; 1.
DR PANTHER; PTHR11949:SF53; INTERFERON REGULATORY FACTOR-3 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00605; IRF; 1.
DR Pfam; PF10401; IRF-3; 1.
DR PRINTS; PR00267; INTFRNREGFCT.
DR SMART; SM00348; IRF; 1.
DR SMART; SM01243; IRF-3; 1.
DR SUPFAM; SSF49879; SMAD/FHA domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS00601; IRF_1; 1.
DR PROSITE; PS51507; IRF_2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000279833}.
FT DOMAIN 4..111
FT /note="IRF tryptophan pentad repeat"
FT /evidence="ECO:0000259|PROSITE:PS51507"
SQ SEQUENCE 467 AA; 53542 MW; E2D56D2CD8008A1C CRC64;
MDIRVRLRPW LESRLNDGWI EGLKWIDREK GIFRIPWKHH SKHTWTEDDA AIFKDWAVVT
GRYREGIDTP DWPMWKTRLR CALNKAPDIQ EVKQRHNLHC EEPFKVYRFV SKTESLWRAN
AIRNASMIFD GIQAGCRFTS WSGSNASSSP MNSPIPLSRR PTLIVQKLSG LKSNTRRFAV
IRRGDGVQHI QSNYRPAYIL QGHQLNRNKI YYNSTSANAT QRLGCDNENM NLDSYANLSP
SSYSEYQAPN NTTVITGGIS LPNRFVPRIG SANQHVQLLP DIMEPEYHQL GVRIQHLSVR
IRDTIVTNPN GCCIYYGRFD EISSPAAPDP IEAQIPHQIS VANKAYVDLL LDNMVKGIIL
TVIHGSIYAE RICKCAVFVY IPTVGGEYIL AKKLGRRLRE KIFDYDQFLF HLDSYRQNQQ
SRPHFEVVLA FGQQLKPGIS TDSLLVWARV ASCRAWFQLH KVSAICS
//
