ID A0A183JHD6_9TREM Unreviewed; 362 AA.
AC A0A183JHD6;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=HECT domain-containing protein {ECO:0000313|WBParaSite:SCUD_0000210901-mRNA-1};
GN ORFNames=SCUD_LOCUS2110 {ECO:0000313|EMBL:VDO72239.1};
OS Schistosoma curassoni.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6186 {ECO:0000313|Proteomes:UP000050789, ECO:0000313|WBParaSite:SCUD_0000210901-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:SCUD_0000210901-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDO72239.1, ECO:0000313|Proteomes:UP000279833}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Dakar {ECO:0000313|EMBL:VDO72239.1}, and Dakar, Senegal
RC {ECO:0000313|Proteomes:UP000279833};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00104}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; UZAK01001925; VDO72239.1; -; Genomic_DNA.
DR STRING; 6186.A0A183JHD6; -.
DR WBParaSite; SCUD_0000210901-mRNA-1; SCUD_0000210901-mRNA-1; SCUD_0000210901.
DR Proteomes; UP000050789; Unplaced.
DR Proteomes; UP000279833; Unassembled WGS sequence.
DR GO; GO:0003723; F:RNA binding; IEA:InterPro.
DR GO; GO:0004842; F:ubiquitin-protein transferase activity; IEA:InterPro.
DR Gene3D; 1.10.1900.10; c-terminal domain of poly(a) binding protein; 1.
DR Gene3D; 3.30.2160.10; Hect, E3 ligase catalytic domain; 1.
DR InterPro; IPR000569; HECT_dom.
DR InterPro; IPR035983; Hect_E3_ubiquitin_ligase.
DR InterPro; IPR036053; PABP-dom.
DR InterPro; IPR002004; PABP_HYD.
DR PANTHER; PTHR46276; E3 UBIQUITIN-PROTEIN LIGASE UBR5; 1.
DR PANTHER; PTHR46276:SF1; E3 UBIQUITIN-PROTEIN LIGASE UBR5; 1.
DR Pfam; PF00632; HECT; 1.
DR Pfam; PF00658; PABP; 1.
DR SMART; SM00119; HECTc; 1.
DR SMART; SM00517; PolyA; 1.
DR SUPFAM; SSF56204; Hect, E3 ligase catalytic domain; 1.
DR SUPFAM; SSF63570; PABC (PABP) domain; 1.
DR PROSITE; PS50237; HECT; 1.
DR PROSITE; PS51309; PABC; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000279833};
KW Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786,
KW ECO:0000256|PROSITE-ProRule:PRU00104}.
FT DOMAIN 28..107
FT /note="PABC"
FT /evidence="ECO:0000259|PROSITE:PS51309"
FT DOMAIN 211..349
FT /note="HECT"
FT /evidence="ECO:0000259|PROSITE:PS50237"
SQ SEQUENCE 362 AA; 40522 MW; 17CE7B3D31761587 CRC64;
SPNRTQDPSD NISRNILLVN YEPSNSIQSS ESNNPVCARH DLANGRSVGG RLFTRIQSLV
RNEHLTARIT GMLLELPSSE HSVLLTNEEA LCNRVDEARA LIAMSDTNDQ NRVERPRTPS
IGLNQPVLER LVNWQGVALT VTGATSVNQQ SNISSSSTIA EVIITEDVER VPLFWQPGLQ
GYYFPRAVPG INLPSNQTCD SVKLAARYSI YRGIGRVIGL CLLTNETCPL HFSRPVLKYI
LGRVVHWHDF AFYDPTTFEG LRQLLLHTSE DFSKSQGSIE DYNLTFSLIP ALEEGGLSST
DAVRQPNDYL YALIPGGDEV EVNESNVFEF VKKYTEFKMR TAVQEPLEVR FLPVFLHFVP
NV
//
