ID A0A183JIZ6_9TREM Unreviewed; 233 AA.
AC A0A183JIZ6;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE RecName: Full=adenosine deaminase {ECO:0000256|ARBA:ARBA00012784};
DE EC=3.5.4.4 {ECO:0000256|ARBA:ARBA00012784};
GN ORFNames=SCUD_LOCUS2671 {ECO:0000313|EMBL:VDO76168.1};
OS Schistosoma curassoni.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6186 {ECO:0000313|Proteomes:UP000050789, ECO:0000313|WBParaSite:SCUD_0000267001-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:SCUD_0000267001-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDO76168.1, ECO:0000313|Proteomes:UP000279833}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Dakar {ECO:0000313|EMBL:VDO76168.1}, and Dakar, Senegal
RC {ECO:0000313|Proteomes:UP000279833};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- COFACTOR:
CC Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC Evidence={ECO:0000256|ARBA:ARBA00001947};
CC -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
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DR EMBL; UZAK01002689; VDO76168.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A183JIZ6; -.
DR STRING; 6186.A0A183JIZ6; -.
DR WBParaSite; SCUD_0000267001-mRNA-1; SCUD_0000267001-mRNA-1; SCUD_0000267001.
DR Proteomes; UP000050789; Unplaced.
DR Proteomes; UP000279833; Unassembled WGS sequence.
DR GO; GO:0004000; F:adenosine deaminase activity; IEA:UniProt.
DR Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR InterPro; IPR001365; A_deaminase_dom.
DR InterPro; IPR006330; Ado/ade_deaminase.
DR InterPro; IPR032466; Metal_Hydrolase.
DR PANTHER; PTHR11409; ADENOSINE DEAMINASE; 1.
DR PANTHER; PTHR11409:SF43; ADENOSINE DEAMINASE; 1.
DR Pfam; PF00962; A_deaminase; 1.
DR SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000279833};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..28
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 29..233
FT /note="adenosine deaminase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5035045855"
FT DOMAIN 15..202
FT /note="Adenosine deaminase"
FT /evidence="ECO:0000259|Pfam:PF00962"
SQ SEQUENCE 233 AA; 26580 MW; E96744F2C7CEC372 CRC64;
MSQKTSNFYS LGYHKYIIIL LLIHEVLARI CEEFVEDCVK RGGLCYVETR YCPFLLTDSK
CSAEEVLKTI LDALNRASKK HGIEVRSILS IMRHMPETAK ETLDLAKNYQ PHGVVAIDIA
GDDSVLKLQR VPEEIVQTFE NAKKANIHRT VHVGENSSAS SVYEAVNNLY AERIGHGYHI
LDDENAYKSL LETGVHFEVR INNNTRHILC LFSKEEKNIF FIGVMNRSKL DNH
//
