ID A0A183JVR1_9TREM Unreviewed; 290 AA.
AC A0A183JVR1;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=Zinc transporter ZIP3 {ECO:0000256|ARBA:ARBA00039395};
DE AltName: Full=Solute carrier family 39 member 3 {ECO:0000256|ARBA:ARBA00042778};
DE AltName: Full=Zrt- and Irt-like protein 3 {ECO:0000256|ARBA:ARBA00041702};
GN ORFNames=SCUD_LOCUS6807 {ECO:0000313|EMBL:VDP07758.1};
OS Schistosoma curassoni.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6186 {ECO:0000313|Proteomes:UP000050789, ECO:0000313|WBParaSite:SCUD_0000680601-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:SCUD_0000680601-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDP07758.1, ECO:0000313|Proteomes:UP000279833}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Dakar {ECO:0000313|EMBL:VDP07758.1}, and Dakar, Senegal
RC {ECO:0000313|Proteomes:UP000279833};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Zn(2+)(in) = Zn(2+)(out); Xref=Rhea:RHEA:29351,
CC ChEBI:CHEBI:29105; Evidence={ECO:0000256|ARBA:ARBA00036307};
CC PhysiologicalDirection=left-to-right; Xref=Rhea:RHEA:29352;
CC Evidence={ECO:0000256|ARBA:ARBA00036307};
CC -!- SUBCELLULAR LOCATION: Apical cell membrane
CC {ECO:0000256|ARBA:ARBA00004424}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004424}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; UZAK01017288; VDP07758.1; -; Genomic_DNA.
DR STRING; 6186.A0A183JVR1; -.
DR WBParaSite; SCUD_0000680601-mRNA-1; SCUD_0000680601-mRNA-1; SCUD_0000680601.
DR Proteomes; UP000050789; Unplaced.
DR Proteomes; UP000279833; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0046873; F:metal ion transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0006829; P:zinc ion transport; IEA:UniProt.
DR InterPro; IPR003689; ZIP.
DR PANTHER; PTHR11040:SF214; ZINC TRANSPORTER ZIP3; 1.
DR PANTHER; PTHR11040; ZINC/IRON TRANSPORTER; 1.
DR Pfam; PF02535; Zip; 2.
PE 4: Predicted;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000279833};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 122..141
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 153..178
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 199..225
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 237..256
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 268..287
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 88..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 290 AA; 31668 MW; 435BE9B058CDBAB5 CRC64;
YLDDNNSNNN VKHNEITANH KLSLEGSQQN NIGYLSSKLM KSNAKRPSKL SNATNTSELT
AVDCSPTSST HSGNDFLLES NITRNHVEHT GHCHDDNNDD HNAHHHSHTH DIKFDTSSFG
SVLRIVLLLC AMSVHSIFEG LAVGLQPTTQ RTLALFTAIL LHKIIIAIGI GVNLATNLNQ
PSTSSGSSFP SRSSYCRLFM YQSIGTLILA CSSPFGVLVG CGLMQQKQSP ILTMSTAVLQ
GLACGTFFFV VFCELLPVEF KEGVKDRMGK FFFLLLGFAV VALYAFLMPE
//
