ID   A0A183KMR5_9TREM        Unreviewed;       734 AA.
AC   A0A183KMR5;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 26.
DE   SubName: Full=Helicase C-terminal domain-containing protein {ECO:0000313|WBParaSite:SCUD_0001634301-mRNA-1};
GN   ORFNames=SCUD_LOCUS16339 {ECO:0000313|EMBL:VDP61370.1};
OS   Schistosoma curassoni.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6186 {ECO:0000313|Proteomes:UP000050789, ECO:0000313|WBParaSite:SCUD_0001634301-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SCUD_0001634301-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDP61370.1, ECO:0000313|Proteomes:UP000279833}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Dakar {ECO:0000313|EMBL:VDP61370.1}, and Dakar, Senegal
RC   {ECO:0000313|Proteomes:UP000279833};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UZAK01038551; VDP61370.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A183KMR5; -.
DR   STRING; 6186.A0A183KMR5; -.
DR   WBParaSite; SCUD_0001634301-mRNA-1; SCUD_0001634301-mRNA-1; SCUD_0001634301.
DR   Proteomes; UP000050789; Unplaced.
DR   Proteomes; UP000279833; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   CDD; cd18791; SF2_C_RHA; 1.
DR   Gene3D; 1.20.120.1080; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR   InterPro; IPR048333; HA2_WH.
DR   InterPro; IPR007502; Helicase-assoc_dom.
DR   InterPro; IPR001650; Helicase_C.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR   PANTHER; PTHR18934:SF119; ATP-DEPENDENT RNA HELICASE A; 1.
DR   Pfam; PF21010; HA2_C; 1.
DR   Pfam; PF04408; HA2_N; 1.
DR   Pfam; PF00271; Helicase_C; 1.
DR   Pfam; PF07717; OB_NTP_bind; 1.
DR   SMART; SM00847; HA2; 1.
DR   SMART; SM00490; HELICc; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   PROSITE; PS51194; HELICASE_CTER; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022806};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022806};
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022806};
KW   Reference proteome {ECO:0000313|Proteomes:UP000279833};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        67..89
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        290..312
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          62..232
FT                   /note="Helicase C-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS51194"
FT   REGION          583..621
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        593..621
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   734 AA;  82710 MW;  C5DFA1315DDB2578 CRC64;
     MVNFVPPPAD EKKRKHRQEL ENATDYAEEN CNLKCDPIYG EAVVRSMGEM IEKEVPFELV
     GALLDKIIGM NIPGAVLIFL PGWNIISLLR KYLQSHSRYG SPSYVILPLH SQIPREDQRL
     VFRSTPSGVR KIVLATNIAE SSITINDVVF VIDFCLSRTK LFTARNNLTS YSTSWASKTN
     LEQRRGRAGR VRPGFAFHLC SRARFDRLEQ HATPEILRTP LHELALLIKL LRLGSVRDFL
     MKALQPPPLD AVIEAEHTLK EMKALDKNDE LTPLGFILAR LPIEPRLGKM LIFACVFNLG
     GAAAVLTSTA SLGCDPFLLP PDHRRLTNQQ RSFAAGYSSD HLAGLNVFQE WTTERTRRGD
     ESADLFCDQH GFNSSALRVI DDAANQLRAI LINLGFPEES LSDAPVNFNL KHNIDCDILS
     TLLVSGLYPN ICFHSDKRKL LTTEGTLALI HKSSVNCMKD IKFTHPFFVF DEKVSIRTQA
     VSCKGLSMVN PIQLMLFGCR SAIWKSDDSN DKGIVVIDDW IPFRMSFMTA ARIFAFRPAL
     EALLVRTCLR PEGVADLREE DQHVINVLRQ LCSPEALKPN ASFDEANNFD SPPRKRFATS
     SNCPLLSGRS HRNKGYENSY SEKQGFGRYT NCPNRPTDPE QVHDIQCGLW QDPQPQFSNP
     RYDHVPVNRF SGNYMGARSF GPSGVGNNFN GSSWNSYGAP TFGGYPYQQQ QFTNDRFVQP
     NQRPSIRPHW GVRY
//