ID   A0A183KU78_9TREM        Unreviewed;       255 AA.
AC   A0A183KU78;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   24-JAN-2024, entry version 28.
DE   SubName: Full=Fork-head domain-containing protein {ECO:0000313|WBParaSite:SCUD_0001862101-mRNA-1};
GN   ORFNames=SCUD_LOCUS18618 {ECO:0000313|EMBL:VDP66382.1};
OS   Schistosoma curassoni.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6186 {ECO:0000313|Proteomes:UP000050789, ECO:0000313|WBParaSite:SCUD_0001862101-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SCUD_0001862101-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDP66382.1, ECO:0000313|Proteomes:UP000279833}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Dakar {ECO:0000313|EMBL:VDP66382.1}, and Dakar, Senegal
RC   {ECO:0000313|Proteomes:UP000279833};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC       ECO:0000256|PROSITE-ProRule:PRU00089}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; UZAK01041269; VDP66382.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A183KU78; -.
DR   STRING; 6186.A0A183KU78; -.
DR   WBParaSite; SCUD_0001862101-mRNA-1; SCUD_0001862101-mRNA-1; SCUD_0001862101.
DR   Proteomes; UP000050789; Unplaced.
DR   Proteomes; UP000279833; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR001766; Fork_head_dom.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR45767; FORKHEAD BOX PROTEIN O; 1.
DR   PANTHER; PTHR45767:SF2; FORKHEAD BOX PROTEIN O; 1.
DR   Pfam; PF00250; Forkhead; 1.
DR   SMART; SM00339; FH; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50039; FORK_HEAD_3; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00089}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00089};
KW   Reference proteome {ECO:0000313|Proteomes:UP000279833}.
FT   DOMAIN          201..249
FT                   /note="Fork-head"
FT                   /evidence="ECO:0000259|PROSITE:PS50039"
FT   DNA_BIND        201..249
FT                   /note="Fork-head"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00089"
FT   REGION          45..77
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          156..196
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        53..77
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   255 AA;  27455 MW;  DF756BC7DF33FEC9 CRC64;
     MSASYIRRDT LVSNPCSLSI LSGSSINANE HKDVSSLSTI RSYPDQAMPL KHSPSGGQLQ
     QGNQGSIHSP KMSPDSTLIQ LSTPNFVSYL NSTTSLGISS GNSITCDSFL RSALLSDGLE
     KQCVGSSTNP HVTHFHDPSA LPNIHPCSLL RPRAMTTSNA SRSGTPVGNT PTSGSSACAS
     APTSTTPVKK SSRRNPWGSE TYSDLISVAI RSYPDKQATL QQIYDFIITH YEYFRERSDP
     TSSAGWKVSK IFCFI
//