ID   A0A183L401_9TREM        Unreviewed;       514 AA.
AC   A0A183L401;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   22-FEB-2023, entry version 25.
DE   SubName: Full=CULLIN_2 domain-containing protein {ECO:0000313|WBParaSite:SCUD_0002206201-mRNA-1};
GN   ORFNames=SCUD_LOCUS22059 {ECO:0000313|EMBL:VDP77555.1};
OS   Schistosoma curassoni.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6186 {ECO:0000313|Proteomes:UP000050789, ECO:0000313|WBParaSite:SCUD_0002206201-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SCUD_0002206201-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDP77555.1, ECO:0000313|Proteomes:UP000279833}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Dakar {ECO:0000313|EMBL:VDP77555.1}, and Dakar, Senegal
RC   {ECO:0000313|Proteomes:UP000279833};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the cullin family.
CC       {ECO:0000256|ARBA:ARBA00006019, ECO:0000256|PROSITE-ProRule:PRU00330,
CC       ECO:0000256|RuleBase:RU003829}.
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DR   EMBL; UZAK01048227; VDP77555.1; -; Genomic_DNA.
DR   STRING; 6186.A0A183L401; -.
DR   WBParaSite; SCUD_0002206201-mRNA-1; SCUD_0002206201-mRNA-1; SCUD_0002206201.
DR   Proteomes; UP000050789; Unplaced.
DR   Proteomes; UP000279833; Unassembled WGS sequence.
DR   GO; GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.
DR   GO; GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
DR   Gene3D; 1.20.1310.10; Cullin Repeats; 5.
DR   InterPro; IPR045093; Cullin.
DR   InterPro; IPR016158; Cullin_homology.
DR   InterPro; IPR036317; Cullin_homology_sf.
DR   InterPro; IPR001373; Cullin_N.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   PANTHER; PTHR11932; CULLIN; 1.
DR   PANTHER; PTHR11932:SF168; CULLIN-3; 1.
DR   Pfam; PF00888; Cullin; 1.
DR   SMART; SM00182; CULLIN; 1.
DR   SUPFAM; SSF75632; Cullin homology domain; 1.
DR   SUPFAM; SSF74788; Cullin repeat-like; 1.
DR   PROSITE; PS50069; CULLIN_2; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000279833}.
FT   DOMAIN          361..514
FT                   /note="Cullin family profile"
FT                   /evidence="ECO:0000259|PROSITE:PS50069"
SQ   SEQUENCE   514 AA;  59435 MW;  872D753DB96D6C79 CRC64;
     MSSGSSARRT EVTNGKVRIK AFPPSIDERY ANQLWDQIKS AIIEIQKKNN SCLSFEELYR
     NAYTLILQKH DHQTAMGMIR DILMYMDRVF VGPHNLDGVY KMGMTVFCDL VIRYPIIREH
     LQKTLLDMVR KERRGEVISR SQIRDACQMF VHLGAGSLCV YLEDFEQPFL EQSREFYRTE
     SENFLAENTS ASLYIKKVEQ RIEEEVRRAH HHLDPSTEPK IVIVLEEELI SRHMETIVGM
     EDSGLTYMLT HDHFTDIAAX XXXXXXXXXX XXXXXXXXXG VLSRVEEGPK IMSNYISLYL
     REQGRNTVRD TGSSTPQQHI QDLLQLRDRA NELLTRALNN QTIFRNQINS DFEYFVNLNP
     RSPEFLSLFI DEKLKRGTKG MTDQDVDAIF DKCIVLFRYL QEKDLFEGYY KKHLAKRLLL
     SKSQSDDQEK IMISKLMAEC GAVYTSKLEG MFKDMAVSKT LMDEFNVVLS NGNHNLNLDL
     CVRVLTTGLW PTQVTNSNEA LPEEADTAFE IYKK
//