ID   A0A183LA14_9TREM        Unreviewed;       486 AA.
AC   A0A183LA14;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=HELP domain-containing protein {ECO:0000313|WBParaSite:SMRZ_0000063801-mRNA-1};
GN   ORFNames=SMRZ_LOCUS639 {ECO:0000313|EMBL:VDO48828.1};
OS   Schistosoma margrebowiei.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=48269 {ECO:0000313|WBParaSite:SMRZ_0000063801-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SMRZ_0000063801-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO48828.1, ECO:0000313|Proteomes:UP000277204}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Zambia {ECO:0000313|EMBL:VDO48828.1,
RC   ECO:0000313|Proteomes:UP000277204};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UZAI01000122; VDO48828.1; -; Genomic_DNA.
DR   STRING; 48269.A0A183LA14; -.
DR   WBParaSite; SMRZ_0000063801-mRNA-1; SMRZ_0000063801-mRNA-1; SMRZ_0000063801.
DR   Proteomes; UP000277204; Unassembled WGS sequence.
DR   CDD; cd21931; TD_EMAP-like; 1.
DR   Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR   InterPro; IPR049813; Elp-1-like_TD.
DR   InterPro; IPR005108; HELP.
DR   InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR   InterPro; IPR036322; WD40_repeat_dom_sf.
DR   PANTHER; PTHR13720:SF50; ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 2; 1.
DR   PANTHER; PTHR13720; WD-40 REPEAT PROTEIN; 1.
DR   Pfam; PF03451; HELP; 1.
DR   SUPFAM; SSF50978; WD40 repeat-like; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000277204}.
FT   DOMAIN          367..410
FT                   /note="HELP"
FT                   /evidence="ECO:0000259|Pfam:PF03451"
FT   REGION          55..163
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          199..222
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          250..310
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          3..30
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        250..272
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        273..290
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   486 AA;  54312 MW;  03EE93ECB5779437 CRC64;
     MHVELMNLEN AGLQDRVIDL EKRSAEQANE LACLRSSLAD CLRRLNLLES ARGMKLHSSS
     QRPVLHNNGS NVTKTNSRTD SSYSSRRHTN SRNPTSTGHQ SKNSRDSSLV VPHSTTTSTT
     AKTRLKSPQS VRLSSSSTTL NNQAVGVSGG TNQTRRNRIT SASSEDRQFN NFNNNKHEGD
     NKTLSMYEYN DMIMSRQSEP ITYQQKSSTL KSNTSSRYYE ASNGPSGYTV FWRSAYDGEL
     DDIYRMNHCQ SPTSQQHQQH SVSMSSSFRK NHTVAPPPPP PPPALPPSSL CIPPNLVRRG
     RPSSGPSSSI YYCANDSDDR SVHLTSTGRS LHPTAWKPGG VAICPTNRET IPSVNKPSCI
     PKFHDDEQLQ GNYLFTSYGY RGRDCRNNLH YLPTGELIYF VAAVVVLYNI EEQCQRHYLE
     HTDDVKCIAI HPDRITVATG QSAGHDKQFG KDSGVKLCAV DEATDHVISI WDWQKSRKIT
     ETKVRY
//