ID A0A183LBI4_9TREM Unreviewed; 351 AA.
AC A0A183LBI4;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE SubName: Full=TGF_BETA_2 domain-containing protein {ECO:0000313|WBParaSite:SMRZ_0000115801-mRNA-1};
GN ORFNames=SMRZ_LOCUS1159 {ECO:0000313|EMBL:VDO50390.1};
OS Schistosoma margrebowiei.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=48269 {ECO:0000313|WBParaSite:SMRZ_0000115801-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:SMRZ_0000115801-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDO50390.1, ECO:0000313|Proteomes:UP000277204}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Zambia {ECO:0000313|EMBL:VDO50390.1,
RC ECO:0000313|Proteomes:UP000277204};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the TGF-beta family.
CC {ECO:0000256|ARBA:ARBA00006656, ECO:0000256|RuleBase:RU000354}.
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DR EMBL; UZAI01000243; VDO50390.1; -; Genomic_DNA.
DR STRING; 48269.A0A183LBI4; -.
DR WBParaSite; SMRZ_0000115801-mRNA-1; SMRZ_0000115801-mRNA-1; SMRZ_0000115801.
DR Proteomes; UP000277204; Unassembled WGS sequence.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0008083; F:growth factor activity; IEA:UniProtKB-KW.
DR CDD; cd08698; TGF_beta_SF; 1.
DR Gene3D; 2.10.90.10; Cystine-knot cytokines; 1.
DR InterPro; IPR029034; Cystine-knot_cytokine.
DR InterPro; IPR001839; TGF-b_C.
DR InterPro; IPR015615; TGF-beta-rel.
DR InterPro; IPR017948; TGFb_CS.
DR PANTHER; PTHR11848:SF298; PROTEIN 60A-RELATED; 1.
DR PANTHER; PTHR11848; TGF-BETA FAMILY; 1.
DR Pfam; PF00019; TGF_beta; 1.
DR PRINTS; PR00669; INHIBINA.
DR SMART; SM00204; TGFB; 1.
DR SUPFAM; SSF57501; Cystine-knot cytokines; 1.
DR PROSITE; PS00250; TGF_BETA_1; 1.
DR PROSITE; PS51362; TGF_BETA_2; 1.
PE 3: Inferred from homology;
KW Growth factor {ECO:0000256|ARBA:ARBA00023030,
KW ECO:0000256|RuleBase:RU000354};
KW Reference proteome {ECO:0000313|Proteomes:UP000277204};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT DOMAIN 222..351
FT /note="TGF-beta family profile"
FT /evidence="ECO:0000259|PROSITE:PS51362"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 351 AA; 41305 MW; D02BBBD3B63EB8D2 CRC64;
MSKFPYSSQP LEERERTDQP PVKLPNPNIF TLKVAEEIDP THISRVTLHV EINGEIRPNS
IFTLWEIYPT LFKPNFLWLN DINDDDDNNN NNNENDDLTA ESLPQIDIND YNEMENDQKF
QSFNLFNDPY RLSMNDFHRM FKLIKPEIAK TMLPENHLTS MITLNITNRM IQWLKYNNIK
IQAYKPLIRY LMIMCNDCDN EQNIIDPKKV VMEIKYRPRL KRQRRSLTKG DETIYNVCRS
NGHHYSCCTQ PLSVKFSDIG WDNWIIHPKS FEPNYCRGSC KVTSTKSLHY DVMDLLLRKN
LSQFGNIQRD DVQSCCHPTQ LTSMSVLYLD SNRELQMHTL HNLIVLGCAC S
//
