ID   A0A183LD18_9TREM        Unreviewed;      1938 AA.
AC   A0A183LD18;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=Helicase ATP-binding domain-containing protein {ECO:0000313|WBParaSite:SMRZ_0000169201-mRNA-1};
GN   ORFNames=SMRZ_LOCUS1693 {ECO:0000313|EMBL:VDO52599.1};
OS   Schistosoma margrebowiei.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=48269 {ECO:0000313|WBParaSite:SMRZ_0000169201-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SMRZ_0000169201-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO52599.1, ECO:0000313|Proteomes:UP000277204}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Zambia {ECO:0000313|EMBL:VDO52599.1,
RC   ECO:0000313|Proteomes:UP000277204};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UZAI01000391; VDO52599.1; -; Genomic_DNA.
DR   STRING; 48269.A0A183LD18; -.
DR   WBParaSite; SMRZ_0000169201-mRNA-1; SMRZ_0000169201-mRNA-1; SMRZ_0000169201.
DR   Proteomes; UP000277204; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR   GO; GO:0140658; F:ATP-dependent chromatin remodeler activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0017025; F:TBP-class protein binding; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 3.40.50.10810; Tandem AAA-ATPase domain; 2.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR014001; Helicase_ATP-bd.
DR   InterPro; IPR044972; Mot1.
DR   InterPro; IPR022707; Mot1_central_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR038718; SNF2-like_sf.
DR   InterPro; IPR000330; SNF2_N.
DR   PANTHER; PTHR36498; TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172; 1.
DR   PANTHER; PTHR36498:SF1; TATA-BINDING PROTEIN-ASSOCIATED FACTOR 172; 1.
DR   Pfam; PF12054; DUF3535; 1.
DR   Pfam; PF00176; SNF2-rel_dom; 2.
DR   SMART; SM00487; DEXDc; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
PE   4: Predicted;
KW   ATP-binding {ECO:0000256|ARBA:ARBA00022806};
KW   Helicase {ECO:0000256|ARBA:ARBA00022806};
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022806};
KW   Nucleotide-binding {ECO:0000256|ARBA:ARBA00022806};
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000277204}.
FT   DOMAIN          1507..1671
FT                   /note="Helicase ATP-binding"
FT                   /evidence="ECO:0000259|PROSITE:PS51192"
SQ   SEQUENCE   1938 AA;  216788 MW;  2DA46AB5E32B2FDA CRC64;
     MSLVRKLNMR KKVLTLIFSF CQSPVHCDTK RIKLDSSSDV TIDKSGLNVQ ATVSVLNQSS
     GHWPLDRMCT TLLGDLWALR WETRHGAASG LRELLSEPRH TKQAGKYIGQ SETEMYNSHY
     QYLEDIVVRV LCTLALDQLS DFISDEVVAP VRETAAQLLG VLSLHLTTEQ VLLVAKHLIF
     LVSLNDEAVT KLCTNIPCQK DNSNASKNSW MIAHGGLLGI KYLLASRKDL KNTLLPHVTP
     CLISRLFGIP IIADNQTVSR QSGHPSSFSV NTLADDEDIR AAAASALLPI IDTIWVESLS
     QYEYDLFVNH VWSLIRNTPS DLSPSTGPVL SLACALTKAE VGKRQFGEQH NSTVKSEDVS
     IYRVNTSEKI MIIAELLHHV SSSIRQSALN TLQCVIESCE NQIESLSADM LHLILDNLFQ
     RILLESCTSI RALVTNLTIK IIQAAKMDCL VQASLRRLDV WLCQVMQPTG IPYPNRFLVP
     CLRSNSDIQL TSELNSNNDE LTSLTVRSTA NINSNIPSSN QQAVFIPQPS YCIGGFQCLT
     ASRSEMESYV LETRISAVRV LAYLCSRICQ YNQLIPVYLL PCISDNSKSS TSSLPSSVNN
     NDHNHINNTS ISVLNYVIGQ LICQLHLKDR LAMQRFISGL LLSSWSLLSP ISSLPTGFGD
     NNDNNSMNSS NKLFNSMNSF YQINYIDKLT YTWSNLLNTS SSTLLSCHLE QLQNLSERVF
     TNIKIDLHDI AKQLRGRLES CLTEVIYYEE ILAPFKLMQE DCRELIRLMK SGGLPVDSQI
     PINGVLTIVH CKTLLQKVAE IIHAEKQHSV SSVIDSSLLD RLHCQLERTR TTVDHCLTLQ
     LYLGNRVELG IACAFANMNW ILPGRLSLLI RPLMDTIRCM KPFMNQSDNA VRSLNSGTDG
     IFQTNSRHNI TSTATSTSSI FGGSNAYGSS SNNSSAVGSC IDILPIGTCV HLQRLAASCL
     ARLLWLEWKM LSINPPSQSS STLLTNKSLL PNTSKAATKV IKNLTSYLIE SDPDFLLSLS
     STSNLSSDAT HQPNEDQSSA DTKIACVNSL STYRLDLVTN TSSSSEAQHQ SSQHRGAYIS
     LSCICYTFIN LYHHEEGNQT CWSSSKSSSS ATMEPIDHQS CHHRLSNVSL NSLRLGMPSL
     WHLFWINPVK IVINYYRQSG ILVENGESME QDGAIYERRG YIYSTLKKLT DEIKVNMYKL
     KSVDLPKSNQ DELLSGLIVL SSCLNVILPC IDPDQKETFC DQKDDISFEQ IIWLASLVIR
     LPSIVYRRVG ARLLADLTLL RPVYTLNILL PLLLLTSNGI FLPTDSSTIC VGTLETFLTI
     VEKFSNMHNS SSYILQSVPP VILDDPLAEP NSKSFSLLSM CRCFMNFVNE QSTLDFESKL
     PNELTTNITI NSNSEDGTNS SLSNNLKLFL PYVVLLLTPT LRLISNPNQH IRSTAGRLFA
     ALLNLLPLES SIPNPEKMKE EFKQIRLEQR EFIDNLLHPD RIQSYNLPIK INGTLRTYQQ
     EGVNWLCFLN RYGLNGVLCD DLGLGKTLQT ICILAGSHHE LKQCSAINNS NEYCISNESV
     VMDTKLDEKF PVSLIICPST LCAHWFHEIQ HFAQTEDLNP LIYGGSPTVR QKLINWNYVV
     LDEGHIIKSS KSKVTRAVKH LVAQHRLILT GTPIQNRVSE LWSLFDFLMP EFLGTEQYFL
     AKFARPVAAS RDIKASKSDQ QAGQLALEKL HRLVLPFMLR RLKEDVMQDL PPKIIQDFAC
     KMTPIQRKLY ESFQKTDEGQ QVMNFVSASS GDFYSECRSS SFNCVSTSHG FHALRYFQAV
     CNHPCLVLKS NHPLLDEIKQ ELRIDSMEQL RAVDYSGKLL ALCRLLTDCG FGSPNSINST
     NVGNSGNTLS STSGTSTSSH YLDSYPGLLS QHRALMFFQT REMLQLTGEM LKKQFPWITA
     TRLDGTVPVN ERHNRVVR
//