ID   A0A183LWT0_9TREM        Unreviewed;       276 AA.
AC   A0A183LWT0;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=Calcium-activated potassium channel BK alpha subunit domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=SMRZ_LOCUS8255 {ECO:0000313|EMBL:VDO80495.1};
OS   Schistosoma margrebowiei.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=48269 {ECO:0000313|WBParaSite:SMRZ_0000825601-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SMRZ_0000825601-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO80495.1, ECO:0000313|Proteomes:UP000277204}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Zambia {ECO:0000313|EMBL:VDO80495.1,
RC   ECO:0000313|Proteomes:UP000277204};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; UZAI01003531; VDO80495.1; -; Genomic_DNA.
DR   STRING; 48269.A0A183LWT0; -.
DR   WBParaSite; SMRZ_0000825601-mRNA-1; SMRZ_0000825601-mRNA-1; SMRZ_0000825601.
DR   Proteomes; UP000277204; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006813; P:potassium ion transport; IEA:InterPro.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR003929; K_chnl_BK_asu.
DR   InterPro; IPR047871; K_chnl_Slo-like.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   InterPro; IPR003148; RCK_N.
DR   PANTHER; PTHR10027; CALCIUM-ACTIVATED POTASSIUM CHANNEL ALPHA CHAIN; 1.
DR   PANTHER; PTHR10027:SF33; CALCIUM-ACTIVATED POTASSIUM CHANNEL SUBUNIT ALPHA-1; 1.
DR   Pfam; PF03493; BK_channel_a; 1.
DR   Pfam; PF02254; TrkA_N; 1.
DR   PRINTS; PR01449; BKCHANNELA.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Potassium {ECO:0000256|ARBA:ARBA00022958};
KW   Potassium channel {ECO:0000256|ARBA:ARBA00022826};
KW   Potassium transport {ECO:0000256|ARBA:ARBA00022538};
KW   Reference proteome {ECO:0000313|Proteomes:UP000277204};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        122..143
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        184..206
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          9..87
FT                   /note="RCK N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02254"
FT   DOMAIN          112..203
FT                   /note="Calcium-activated potassium channel BK alpha
FT                   subunit"
FT                   /evidence="ECO:0000259|Pfam:PF03493"
SQ   SEQUENCE   276 AA;  31606 MW;  251678E76C3C7B9C CRC64;
     MLFCNSCRID PDISLTALLQ RESTTMKFLK GSVTLPEDLE RAKVRTAEAV IILSDKCSQT
     PVEDDWKNLM CVVSIKNLYP NIRIICELML IESKVWMSNI PGWKEHESDQ FDRAVCLTQM
     KLGLLALNCV SNGISTLLCN FIMRDSVPTA AVRKTLPRWI NEYFQGTKYK LYTVKLSHAF
     DGMVFQQLVG FAMEFWGLLL LAVQVYTNND KKTQMIINPG VRVRINTHRM RAVVLAKNLI
     EAQRLRTFSI DGQIMFDNYG QLIFSSLSRN QGKYIT
//