ID A0A183MIW3_9TREM Unreviewed; 827 AA.
AC A0A183MIW3;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Calponin-homology (CH) domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SMRZ_LOCUS15988 {ECO:0000313|EMBL:VDP19667.1};
OS Schistosoma margrebowiei.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=48269 {ECO:0000313|WBParaSite:SMRZ_0001598901-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:SMRZ_0001598901-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDP19667.1, ECO:0000313|Proteomes:UP000277204}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Zambia {ECO:0000313|EMBL:VDP19667.1,
RC ECO:0000313|Proteomes:UP000277204};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; UZAI01017039; VDP19667.1; -; Genomic_DNA.
DR STRING; 48269.A0A183MIW3; -.
DR WBParaSite; SMRZ_0001598901-mRNA-1; SMRZ_0001598901-mRNA-1; SMRZ_0001598901.
DR Proteomes; UP000277204; Unassembled WGS sequence.
DR Gene3D; 1.10.418.10; Calponin-like domain; 1.
DR InterPro; IPR022735; bMERB_dom.
DR InterPro; IPR001715; CH_dom.
DR InterPro; IPR036872; CH_dom_sf.
DR InterPro; IPR019448; NT-C2.
DR PANTHER; PTHR23167; CALPONIN HOMOLOGY DOMAIN-CONTAINING PROTEIN DDB_G0272472-RELATED; 1.
DR PANTHER; PTHR23167:SF62; EPS15 HOMOLOGY DOMAIN CONTAINING PROTEIN-BINDING PROTEIN 1, ISOFORM F; 1.
DR Pfam; PF12130; bMERB_dom; 1.
DR Pfam; PF00307; CH; 1.
DR Pfam; PF10358; NT-C2; 1.
DR SMART; SM00033; CH; 1.
DR SMART; SM01203; DUF3585; 1.
DR SUPFAM; SSF47576; Calponin-homology domain, CH-domain; 1.
DR PROSITE; PS51848; BMERB; 1.
DR PROSITE; PS51840; C2_NT; 1.
DR PROSITE; PS50021; CH; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000277204}.
FT DOMAIN 7..168
FT /note="C2 NT-type"
FT /evidence="ECO:0000259|PROSITE:PS51840"
FT DOMAIN 321..427
FT /note="Calponin-homology (CH)"
FT /evidence="ECO:0000259|PROSITE:PS50021"
FT DOMAIN 686..827
FT /note="BMERB"
FT /evidence="ECO:0000259|PROSITE:PS51848"
FT REGION 467..494
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 692..726
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 467..489
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 827 AA; 93051 MW; CC182C6096AB917F CRC64;
MSVWRRLQRV GKKAAKFQIT ASLHELNIEC SRQYSPGNLV VVWSRRSRRY SSKSFEPVKS
SGNSNSFKYV WSMPENIEFV TTLYRNEKAI QFEEKEWICQ IEDVGAKTSG LLSASTPSVR
RRVLATRQID IAEFVSDLPV QTNLKVVMRL ASKKLISATV LLTLNSVIVK AGEATDEDMI
SIASLMSLSR TGSFNVGSGV TINDLGGVAA FSPTTARLSN VDDLNSHSFS NSTFHTDLSE
LTAKLQSLER RQIDPLVESP IKANGNFSDY SSELDNSKIT LNSSKNQDSL SSTVDDMLAK
PLIPTFDKTI PNSTELKPIS TQSRYDLLLW CQLVTKSYDN IQIVDLTTSF QNGLAFCAIL
HHFFPDRIDY DSLSSENPLQ NCRLAFDVAS KLGVPRVLDP SEVVSKSRSP DLLSMMTYLH
QIRTFCCERT KNNDENSPST NDNLVLNGIF EQCIKTNNSE TNHSLQIVEN PPDENSNNAK
NNLTNPDKAV RSTPKKKIPL MNYEHMLAKA RSLLQQSRLN YLAPTNRPGA LPPLAHPRKP
HPISGSLTAI HSTDENFNRN PVTEESLRNI TLTDGQNHRL TDTKLCTSTI CIPNVDTSLN
SISKPFRFST SNIFPTLSKP PQSTVDTRFS PEQMKVRRLR LSQMNLFASG RGSGAPVPIR
IGEHHLDNKT DNRTHVSTSV SSSANNSSSN ALLSVSNYIS NEQAELEEAQ KELDKEAAVL
EQRLRQQMAY EPGTSLEEEL LRRWFILVNK KNALIHRGFQ LSIMEKEDDL KKKMKMLQDE
LRSILSVEDY LKTDNDRRRE DLLLQDLVRL VNERDDIIQE LDLHEKV
//
