ID   A0A183MY77_9TREM        Unreviewed;       980 AA.
AC   A0A183MY77;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 32.
DE   RecName: Full=Intersectin-1 {ECO:0008006|Google:ProtNLM};
GN   ORFNames=SMRZ_LOCUS21002 {ECO:0000313|EMBL:VDP37924.1};
OS   Schistosoma margrebowiei.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=48269 {ECO:0000313|WBParaSite:SMRZ_0002100301-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SMRZ_0002100301-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDP37924.1, ECO:0000313|Proteomes:UP000277204}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Zambia {ECO:0000313|EMBL:VDP37924.1,
RC   ECO:0000313|Proteomes:UP000277204};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UZAI01018537; VDP37924.1; -; Genomic_DNA.
DR   STRING; 48269.A0A183MY77; -.
DR   WBParaSite; SMRZ_0002100301-mRNA-1; SMRZ_0002100301-mRNA-1; SMRZ_0002100301.
DR   Proteomes; UP000277204; Unassembled WGS sequence.
DR   GO; GO:0005509; F:calcium ion binding; IEA:InterPro.
DR   CDD; cd00052; EH; 1.
DR   CDD; cd00174; SH3; 1.
DR   Gene3D; 1.10.238.10; EF-hand; 2.
DR   Gene3D; 2.30.30.40; SH3 Domains; 4.
DR   InterPro; IPR011992; EF-hand-dom_pair.
DR   InterPro; IPR018247; EF_Hand_1_Ca_BS.
DR   InterPro; IPR002048; EF_hand_dom.
DR   InterPro; IPR000261; EH_dom.
DR   InterPro; IPR036028; SH3-like_dom_sf.
DR   InterPro; IPR001452; SH3_domain.
DR   PANTHER; PTHR11216:SF170; DYNAMIN ASSOCIATED PROTEIN 160, ISOFORM D; 1.
DR   PANTHER; PTHR11216; EH DOMAIN; 1.
DR   Pfam; PF12763; EF-hand_4; 1.
DR   Pfam; PF00018; SH3_1; 2.
DR   Pfam; PF14604; SH3_9; 1.
DR   PRINTS; PR00452; SH3DOMAIN.
DR   SMART; SM00027; EH; 2.
DR   SMART; SM00326; SH3; 4.
DR   SUPFAM; SSF47473; EF-hand; 2.
DR   SUPFAM; SSF50044; SH3-domain; 4.
DR   PROSITE; PS00018; EF_HAND_1; 2.
DR   PROSITE; PS50222; EF_HAND_2; 1.
DR   PROSITE; PS50031; EH; 1.
DR   PROSITE; PS50002; SH3; 3.
PE   4: Predicted;
KW   Calcium {ECO:0000256|ARBA:ARBA00022837};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Reference proteome {ECO:0000313|Proteomes:UP000277204};
KW   SH3 domain {ECO:0000256|ARBA:ARBA00022443, ECO:0000256|PROSITE-
KW   ProRule:PRU00192}.
FT   DOMAIN          123..204
FT                   /note="EH"
FT                   /evidence="ECO:0000259|PROSITE:PS50031"
FT   DOMAIN          156..191
FT                   /note="EF-hand"
FT                   /evidence="ECO:0000259|PROSITE:PS50222"
FT   DOMAIN          557..620
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          810..870
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   DOMAIN          926..980
FT                   /note="SH3"
FT                   /evidence="ECO:0000259|PROSITE:PS50002"
FT   REGION          215..245
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          295..334
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          405..501
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   980 AA;  110641 MW;  CAA91758894D97F9 CRC64;
     LAEWDRWVIT TDDRVKHDAQ FQFLKPVGGY ITDMDMDGKM DKKEFSIAMF LIKKTLEGLP
     LPPTLPPGLK KDPQPAFITS GVTLSLSLVS DSGHNGLCSA SSNGQDSNPA STAYQDWIIT
     STNRPRYRLL FNQHDRNKRG FLTGVEARSI LSQYGLPNPI LAHIWNLADL DKNGNLNCDE
     FCIAIFLIEK AISGSQLPNT LPSEWSEDCI LSASSPNKTM SSAYSKSTSE PPGRSSTPGN
     LDESVISKTL SFEDKRRENF RQGQAELDRR KQELAEKMRL DEEIRLENER LEREKQQKLR
     MEKERQQAAE AEKQAELSRQ LEAQREQRRR QAVEHRMKAA RDAEKQRQIE SERIRTDALL
     KERNHIQTLL EQAVAHRASL LESASSQQQR LLELDSRLTV AQTEVDSHKT SINEMRSKRD
     AYERDIRDMT EQVEAAKAEL THWQREKEQL SLRMAAGVDM NPVMEQYKTL QSMREARIKT
     IEQLRNKLNE LDQNMTQQGH ELATRRNKID DSQDRVTRTM LDLVDLRHSV EQKMQAYKLK
     RKSTDLSIST STTIGSTQKE LYEAMFDFTA RHPDELSFTT GTLIDVFVNA PTNVGPGWLY
     GQINDKVGLF PETYVRKKVD GKIDPFDPFG VHKITNTSVS SGMATTTIST TINTLNTISV
     INTIDSRYLS NAVNFKSMIF NSLTEPAIDN LVGSETTPTT KLNDTTFSNN DFYGEVQQNW
     NASMSTITLP ENIPTDQFLT LTVDDRVKII KENDNNKEWY FGEITDKSDI VKKGWFPACC
     LKPFTKSNTS NIKNGLNISS SSNSLSKQPD ILFSCIALYP YESNVSGDLN LSVGDLIRVC
     VIKDDWWEGI CERTKLKGLF PANYVRKLSS EARNTVDGRK NPPSLSKIIP ISSPKLMEAN
     SNNCMASLLS SSNTSSTSSS GVIVCTQPEF ARVIAPYKAT SAGQLTLQPG QVVQLRKRSP
     KGWWEGELQV ISKVSNRFVT
//