ID A0A183N486_9TREM Unreviewed; 403 AA.
AC A0A183N486;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=Beta-1,4-galactosyltransferase {ECO:0000256|RuleBase:RU368121};
DE EC=2.4.1.- {ECO:0000256|RuleBase:RU368121};
GN ORFNames=SMRZ_LOCUS23111 {ECO:0000313|EMBL:VDP45875.1};
OS Schistosoma margrebowiei.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=48269 {ECO:0000313|WBParaSite:SMRZ_0002311201-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:SMRZ_0002311201-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDP45875.1, ECO:0000313|Proteomes:UP000277204}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Zambia {ECO:0000313|EMBL:VDP45875.1,
RC ECO:0000313|Proteomes:UP000277204};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Catalyses the transfer of galactose onto proteins or lipids.
CC {ECO:0000256|RuleBase:RU368121}.
CC -!- PATHWAY: Protein modification; protein glycosylation.
CC {ECO:0000256|RuleBase:RU368121}.
CC -!- SIMILARITY: Belongs to the glycosyltransferase 7 family.
CC {ECO:0000256|RuleBase:RU368121}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; UZAI01019516; VDP45875.1; -; Genomic_DNA.
DR STRING; 48269.A0A183N486; -.
DR WBParaSite; SMRZ_0002311201-mRNA-1; SMRZ_0002311201-mRNA-1; SMRZ_0002311201.
DR UniPathway; UPA00378; -.
DR Proteomes; UP000277204; Unassembled WGS sequence.
DR GO; GO:0016757; F:glycosyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR GO; GO:0006486; P:protein glycosylation; IEA:UniProtKB-UniRule.
DR InterPro; IPR003859; Galactosyl_T.
DR InterPro; IPR027995; Galactosyl_T_N.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR19300; BETA-1,4-GALACTOSYLTRANSFERASE; 1.
DR PANTHER; PTHR19300:SF62; BETA-1,4-N-ACETYLGALACTOSAMINYLTRANSFERASE; 1.
DR Pfam; PF13733; Glyco_transf_7N; 1.
DR SUPFAM; SSF53448; Nucleotide-diphospho-sugar transferases; 1.
PE 3: Inferred from homology;
KW Glycoprotein {ECO:0000256|RuleBase:RU368121};
KW Glycosyltransferase {ECO:0000256|RuleBase:RU368121};
KW Reference proteome {ECO:0000313|Proteomes:UP000277204};
KW Signal-anchor {ECO:0000256|RuleBase:RU368121};
KW Transferase {ECO:0000256|RuleBase:RU368121};
KW Transmembrane {ECO:0000256|RuleBase:RU368121}.
FT DOMAIN 88..160
FT /note="Galactosyltransferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF13733"
FT REGION 253..302
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 269..285
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 403 AA; 46434 MW; 1EE8C756C8D0FE2B CRC64;
METGEKDCPG QSWMKNPVGH VKTPNKALFW PQIQYKYALS QPIDFISPNS SLENFIPQQI
FGSFYTKYNA TKINSYAVSS NSLRYIIDKK NHTINYTTPI IWSPLGCLPS LSSAIIIPYR
KREQHLRVLT DHLHGFLRHQ RIPYTIFIIE QYNFYEMNKN YPREIHIQNG KTIHNRSALS
NGKEENSKLE RNLTIHWCES EMSYHELSRE YTGVDIRNNE LQNNNYLAAP GGQLRPAISE
VEGLDRYAKQ CLEERSVTPP ERNGYMNGHS AKSDANHVSS ESFSSFKRHP THKNDQKNVQ
KQPESLTVFE KLCQKFSKDA TYKNEIRAGK RLGFYRFVLD IGRGNFSKVK LALHSLVNRF
QVSASLTMQS DDSHNVCPIH LHRFFLIFAS VGASLFSRTI GCC
//
