ID A0A183N4X2_9TREM Unreviewed; 635 AA.
AC A0A183N4X2;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=TOG domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=SMRZ_LOCUS23347 {ECO:0000313|EMBL:VDP46853.1};
OS Schistosoma margrebowiei.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=48269 {ECO:0000313|WBParaSite:SMRZ_0002334801-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:SMRZ_0002334801-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDP46853.1, ECO:0000313|Proteomes:UP000277204}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Zambia {ECO:0000313|EMBL:VDP46853.1,
RC ECO:0000313|Proteomes:UP000277204};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the phosphatase 2A regulatory subunit A family.
CC {ECO:0000256|ARBA:ARBA00038332}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; UZAI01019654; VDP46853.1; -; Genomic_DNA.
DR STRING; 48269.A0A183N4X2; -.
DR WBParaSite; SMRZ_0002334801-mRNA-1; SMRZ_0002334801-mRNA-1; SMRZ_0002334801.
DR Proteomes; UP000277204; Unassembled WGS sequence.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR000357; HEAT.
DR InterPro; IPR021133; HEAT_type_2.
DR PANTHER; PTHR10648:SF4; PROTEIN PHOSPHATASE 2 (FORMERLY 2A), REGULATORY SUBUNIT A, BETA ISOFORM-RELATED; 1.
DR PANTHER; PTHR10648; SERINE/THREONINE-PROTEIN PHOSPHATASE PP2A 65 KDA REGULATORY SUBUNIT; 1.
DR Pfam; PF02985; HEAT; 4.
DR SUPFAM; SSF48371; ARM repeat; 1.
DR PROSITE; PS50077; HEAT_REPEAT; 7.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000277204};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT REPEAT 87..125
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 164..202
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 289..327
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 367..405
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 467..505
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 506..542
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REPEAT 545..583
FT /note="HEAT"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00103"
FT REGION 195..224
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 197..224
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 635 AA; 70776 MW; 8267723C4C4E6FA9 CRC64;
MESERDEDYP IGVLIEELRG EDLHVRLHSI RKISTIALAL GPEKTRSQLI PFLTETIYDE
DEVLLTLAEQ IGTLVPYVGG PEYAHSLLPP LESLAAVEET VVRDRAVEAL RKLAPDHTTE
AMEKYFNPLL HRLATGDWFT SRTSACALFS VVYPRVRSSK RWELLDFLRR LAKDETPMVR
RAVAARLGEL ALAMSAGQSS EKPSADGEKS SQISEHNSSN MTTSITESKI LTNEVVSLNS
GHFGCGVAAD ERLTNDSVAE KSSTLANPLQ SDDFTLDPEK ERSYIITIIV PLFVRLVDDE
QESVRLMAVE SIVQLAQALG PEESEGYLID LIQQATTDRS WRVRCVVADK FTEIQTAMGL
RVSRERLVPF FMKLLHDEEA EVRAFAAGKV KAFAKCLLGL PIDADINTTN KTTNSDTKDC
KNSSTTITLD NKMMEIDEKF DSVNNLNDND NNNNGLASKD EIIMLQLLPA IKNLTNESNT
HVKSSLANAI LGLAPLIGKN LTIEHLLPIF LAQLNDDNPE VRLNVISNLE QVNSIIGIDH
LTINLLPAII QLAEDPKWRV RLAIIEYMPL LAEQLGLEFF NNQLIDLCLS WLIDQVYAIR
EAAVENLVNL CKKFGSEWAS QYFIPKVSNK GIYSS
//
