ID   A0A183NEE9_9TREM        Unreviewed;       850 AA.
AC   A0A183NEE9;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=ubiquitinyl hydrolase 1 {ECO:0000256|ARBA:ARBA00012759};
DE            EC=3.4.19.12 {ECO:0000256|ARBA:ARBA00012759};
GN   ORFNames=SMTD_LOCUS485 {ECO:0000313|EMBL:VDO70661.1};
OS   Schistosoma mattheei.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=31246 {ECO:0000313|WBParaSite:SMTD_0000048401-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SMTD_0000048401-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO70661.1, ECO:0000313|Proteomes:UP000269396}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Denwood {ECO:0000313|EMBL:VDO70661.1}, and Denwood, Zambia
RC   {ECO:0000313|Proteomes:UP000269396};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the peptidase C64 family.
CC       {ECO:0000256|ARBA:ARBA00005865}.
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DR   EMBL; UZAL01000427; VDO70661.1; -; Genomic_DNA.
DR   STRING; 31246.A0A183NEE9; -.
DR   WBParaSite; SMTD_0000048401-mRNA-1; SMTD_0000048401-mRNA-1; SMTD_0000048401.
DR   Proteomes; UP000269396; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR   CDD; cd22767; OTU_ZRANB1; 1.
DR   Gene3D; 1.25.40.560; -; 1.
DR   Gene3D; 4.10.1060.10; Zinc finger, RanBP2-type; 2.
DR   InterPro; IPR003323; OTU_dom.
DR   InterPro; IPR001876; Znf_RanBP2.
DR   InterPro; IPR036443; Znf_RanBP2_sf.
DR   InterPro; IPR049768; ZRANB1_OTU.
DR   PANTHER; PTHR13367; UBIQUITIN THIOESTERASE; 1.
DR   PANTHER; PTHR13367:SF28; UBIQUITIN THIOESTERASE ZRANB1; 1.
DR   Pfam; PF02338; OTU; 1.
DR   Pfam; PF00641; zf-RanBP; 1.
DR   SMART; SM00547; ZnF_RBZ; 3.
DR   SUPFAM; SSF90209; Ran binding protein zinc finger-like; 2.
DR   PROSITE; PS50802; OTU; 1.
DR   PROSITE; PS01358; ZF_RANBP2_1; 2.
DR   PROSITE; PS50199; ZF_RANBP2_2; 2.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000269396};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737};
KW   Ubl conjugation pathway {ECO:0000256|ARBA:ARBA00022786};
KW   Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833};
KW   Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW   ProRule:PRU00322}.
FT   DOMAIN          2..32
FT                   /note="RanBP2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50199"
FT   DOMAIN          119..148
FT                   /note="RanBP2-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50199"
FT   DOMAIN          547..704
FT                   /note="OTU"
FT                   /evidence="ECO:0000259|PROSITE:PS50802"
FT   REGION          712..752
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   850 AA;  94255 MW;  DEED98859396B140 CRC64;
     MDVGAKWPCA VCTYDNWPAA FKCTLCGTSR SSTLIEDEMQ RLHLSSKDSE KIDESCAEAV
     FDSTQLIKCQ SCTYLNQRQN FKCEQCFQVL CDSPVLDAEV SKQASSTWLS SSTTTSLSPS
     GKWTCIECTY ENWPKSKHCV MCFASPPQPI CVVDYEDTES KNSNSTCVSS NSSSLNCNRR
     PKSNISYNTP LTSRDRLWLS ACVAVVNGDV APVERYILGN GRIERKLTKH ECRCLNSYMQ
     STTICDISTT FSSIDHSPKR FDDANLSQLP GSSCYSHKTT IPSCESGIAC SNLDYISSGY
     KFRSGWTLVD LALRFCRTDL INLFIALIGL QATSSAISVG SGSKHSTLPV NSSSTASVIT
     SSNSTTITTN VTVSVTTSNT FSNNSLRNST LNPPFQDTQQ THSRNIQVNR KLSSPLTGNQ
     IHPSLQLILN RTPGNINKTQ VTRSKWMPCQ ASPHIAAELR DLLAKTVKHC KGDFPCAYFS
     EWGTFALPYS ITKFPAPVKQ LLHSASTNSL TNSVTEFFFS MLTVELEDEA KAINWWFIPG
     QKQSSRLFAL WNRTAGDCLL DSVLQACWGV FDRENCLRRT LADSLQNCEA NFYPRWRDYE
     ALQAACHYIL DEDQCRRDWE NVLTAACQPR EALEQIHIFA LSHVLRRPII VYGVKYIKNY
     RGEPIGIANF QGIYLPLLWE KCSCSRNPIV LGFTRGHFTA LVPIEPCPLS SSGVSNESNA
     DTNQTTGVIF SPYASPPTSS RKHSPTPLDE TSNYTQVPLT TVPLSETQLV SSTEPSLVSC
     GTTLPGAIAQ QNAFVYLPLV DKQGVLLPIH FTTEKEVKYV LNSILKNKDN HCEAVMLGYS
     SGTIFFNQIV
//