ID   A0A183NGJ0_9TREM        Unreviewed;       240 AA.
AC   A0A183NGJ0;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=adenosine deaminase {ECO:0000256|ARBA:ARBA00012784};
DE            EC=3.5.4.4 {ECO:0000256|ARBA:ARBA00012784};
GN   ORFNames=SMTD_LOCUS1225 {ECO:0000313|EMBL:VDO76465.1};
OS   Schistosoma mattheei.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=31246 {ECO:0000313|WBParaSite:SMTD_0000122501-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SMTD_0000122501-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO76465.1, ECO:0000313|Proteomes:UP000269396}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Denwood {ECO:0000313|EMBL:VDO76465.1}, and Denwood, Zambia
RC   {ECO:0000313|Proteomes:UP000269396};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|ARBA:ARBA00001947};
CC   -!- SIMILARITY: Belongs to the metallo-dependent hydrolases superfamily.
CC       Adenosine and AMP deaminases family. {ECO:0000256|ARBA:ARBA00006676}.
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DR   EMBL; UZAL01001294; VDO76465.1; -; Genomic_DNA.
DR   STRING; 31246.A0A183NGJ0; -.
DR   WBParaSite; SMTD_0000122501-mRNA-1; SMTD_0000122501-mRNA-1; SMTD_0000122501.
DR   Proteomes; UP000269396; Unassembled WGS sequence.
DR   GO; GO:0004000; F:adenosine deaminase activity; IEA:UniProt.
DR   Gene3D; 3.20.20.140; Metal-dependent hydrolases; 1.
DR   InterPro; IPR001365; A_deaminase_dom.
DR   InterPro; IPR006330; Ado/ade_deaminase.
DR   InterPro; IPR032466; Metal_Hydrolase.
DR   PANTHER; PTHR11409; ADENOSINE DEAMINASE; 1.
DR   PANTHER; PTHR11409:SF43; ADENOSINE DEAMINASE; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   SUPFAM; SSF51556; Metallo-dependent hydrolases; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000269396}.
FT   DOMAIN          45..218
FT                   /note="Adenosine deaminase"
FT                   /evidence="ECO:0000259|Pfam:PF00962"
SQ   SEQUENCE   240 AA;  27112 MW;  00FB137476524871 CRC64;
     MKLVLNPLVN TSSPTITSTL LTSVQGFLSF TQHLFSNKIT LKKFVEDCVK RGGLCYVETR
     YCPFLLTDSK CTAEEVLKTI LDALNRASKK HGIEVRSILS IMRHMPETAK ETLELAKNYQ
     PHGVVAIDIA DMLVGAEFLK LQRVPEEIVQ TFENAKKANI HRTVHVGENS PASSVYEAVN
     NLYAERIGHG YHILDDENAY KSLLETGVHF EVRINNNTQH ILCLFSKEKK DIFSLELYCL
//