ID   A0A183NJF6_9TREM        Unreviewed;       220 AA.
AC   A0A183NJF6;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 21.
DE   SubName: Full=Dus domain-containing protein {ECO:0000313|WBParaSite:SMTD_0000224101-mRNA-1};
GN   ORFNames=SMTD_LOCUS2241 {ECO:0000313|EMBL:VDO85335.1};
OS   Schistosoma mattheei.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=31246 {ECO:0000313|WBParaSite:SMTD_0000224101-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SMTD_0000224101-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDO85335.1, ECO:0000313|Proteomes:UP000269396}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Denwood {ECO:0000313|EMBL:VDO85335.1}, and Denwood, Zambia
RC   {ECO:0000313|Proteomes:UP000269396};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Catalyzes the synthesis of dihydrouridine, a modified base
CC       found in the D-loop of most tRNAs. {ECO:0000256|ARBA:ARBA00002468}.
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DR   EMBL; UZAL01002934; VDO85335.1; -; Genomic_DNA.
DR   STRING; 31246.A0A183NJF6; -.
DR   WBParaSite; SMTD_0000224101-mRNA-1; SMTD_0000224101-mRNA-1; SMTD_0000224101.
DR   Proteomes; UP000269396; Unassembled WGS sequence.
DR   CDD; cd02801; DUS_like_FMN; 1.
DR   Gene3D; 3.20.20.70; Aldolase class I; 1.
DR   InterPro; IPR013785; Aldolase_TIM.
DR   InterPro; IPR035587; DUS-like_FMN-bd.
DR   PANTHER; PTHR11082; TRNA-DIHYDROURIDINE SYNTHASE; 1.
DR   PANTHER; PTHR11082:SF5; TRNA-DIHYDROURIDINE(16_17) SYNTHASE [NAD(P)(+)]-LIKE; 1.
DR   Pfam; PF01207; Dus; 1.
DR   SUPFAM; SSF51395; FMN-linked oxidoreductases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000269396}.
FT   DOMAIN          94..201
FT                   /note="DUS-like FMN-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01207"
SQ   SEQUENCE   220 AA;  25022 MW;  EF78FF06E69143DE CRC64;
     MLSYNAVQKI KTLIALYFFQ NRIVSHKQPE DLNQICIRSI YHTASLMSSS VHGHINYEVK
     SFLLLCDCYG FNIYILYVTS FLSKVNIYFL SRFVNLLVSR ASLELNVPVT CKIRIFSDVE
     RTVQYAKLLE AAGASMLTVH GRTREMKGQK TGLADWNQIR AVKEAVKIPV IANGNIQYLS
     DVHQCLDSTK ADAVMSAGFC LSKMLFISFS EMYFFKAIVR
//