ID   A0A183NS14_9TREM        Unreviewed;      1530 AA.
AC   A0A183NS14;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=GON domain-containing protein {ECO:0000313|WBParaSite:SMTD_0000489901-mRNA-1};
GN   ORFNames=SMTD_LOCUS4900 {ECO:0000313|EMBL:VDP25792.1};
OS   Schistosoma mattheei.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=31246 {ECO:0000313|WBParaSite:SMTD_0000489901-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SMTD_0000489901-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDP25792.1, ECO:0000313|Proteomes:UP000269396}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Denwood {ECO:0000313|EMBL:VDP25792.1}, and Denwood, Zambia
RC   {ECO:0000313|Proteomes:UP000269396};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UZAL01026764; VDP25792.1; -; Genomic_DNA.
DR   STRING; 31246.A0A183NS14; -.
DR   WBParaSite; SMTD_0000489901-mRNA-1; SMTD_0000489901-mRNA-1; SMTD_0000489901.
DR   Proteomes; UP000269396; Unassembled WGS sequence.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR   GO; GO:0004222; F:metalloendopeptidase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   Gene3D; 2.60.120.830; -; 1.
DR   Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 2.
DR   InterPro; IPR045371; ADAMTS_CR_3.
DR   InterPro; IPR012314; Pept_M12B_GON-ADAMTSs.
DR   InterPro; IPR000884; TSP1_rpt.
DR   InterPro; IPR036383; TSP1_rpt_sf.
DR   PANTHER; PTHR13723:SF200; ADAM METALLOPEPTIDASE WITH THROMBOSPONDIN TYPE 1 MOTIF B, ISOFORM B; 1.
DR   PANTHER; PTHR13723; ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE; 1.
DR   Pfam; PF19236; ADAMTS_CR_3; 1.
DR   Pfam; PF08685; GON; 1.
DR   Pfam; PF19030; TSP1_ADAMTS; 5.
DR   Pfam; PF00090; TSP_1; 1.
DR   SMART; SM00209; TSP1; 5.
DR   SUPFAM; SSF82895; TSP-1 type 1 repeat; 6.
DR   PROSITE; PS51046; GON; 1.
DR   PROSITE; PS50092; TSP1; 5.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000269396};
KW   Secreted {ECO:0000256|ARBA:ARBA00022525}.
FT   DOMAIN          1359..1530
FT                   /note="GON"
FT                   /evidence="ECO:0000259|PROSITE:PS51046"
SQ   SEQUENCE   1530 AA;  173202 MW;  480F7932303E7888 CRC64;
     MQLDDLDFAD DLALLSQSQQ QIQEKTTSVV AASASVGLII HKGKSKILRN NTACINPVAI
     DGEDLEDVKT FTYLGSIIDE HGGSDADVKA RVGKTRAAYL QLRNVWNPNQ LSTNTKWCIQ
     GRCVSTNENP TPLHGNWGEW GSWSKCSRSC GGGVQFSERE CNNPEWTGNV ESIKPKVGEP
     TSCNLICLYN SHSVSHGFSL PDGTPCYTQR DDICIKGKCW ETGCDGILGS RLRFDRCRVC
     GGDNSTCEEI KGVFNGSTLT PPGTYPRGLI TAVRIPRGVT NAFVRKVSDR IIPYSSDSYD
     DFMLLIFEEL KTQIRRGETH EPFAGAELYY SGSRSREEIV SITGRLNKDV NIVIRVENSH
     TTQSLPRVEY SYFIDKSQKN NSLYFIAESE ARLAEDRINR RTGRSQDTHS SYETVDKLIN
     PVQHKPSELD NRKIKNEKPK IYFVWRISEL PTGCTTCAGN VTTPAECYPL VPKDTEQSQF
     SQFDLLRPVA DYLCASMPKP PSVFRRCSDY CGVRWSAKPV LTGRTSNGIH DFYTSSCSAR
     CNEGHEAVEY VCEEYIVPAE QKNKSKGIWR VAQLGELVCH KAGLGKAPPQ PAYVTCKGSC
     YPVYWILSNW TECNNSCGDG TRKRILYCQD EIGQNWPLNE CMTYGESMIH HSKAPKQSVT
     IHSAQEIILL YQQNNNFQLS LEHNLYIEQY DECFSLSKCR NDINWSTTKW SECEPLDEQM
     KSNCRLVDNI TDRKDLINKI IGVRYRNVSC IIDNNDNYHN SLNKYIMPDQ LTSSYFMKRI
     QLDLNFCRKA SMLGELVEEP YGREACTQPK CYRWGNGQLS AVNKANLAIF QLLCTLNSLG
     VVLPVSSNRY LGLQLISLLL AYVRPCSVNC GSGVKQTRIS CESVILKDDL DTSSNEKKVV
     LQGIHIVDND KCLQNLQYMP RLFTDKTNDT IFVETVERRI NNDQEMIPIK VDNINEPVVL
     TCNEAPCDLR LPAWRTTSWS ACSSSCGLGV RQRKVMCVVE TQNANLHKRH SVSYTSIFTA
     SRSNIEVVDS QICYNALLPV PTEQETCLEA PCPIWHAEEW QECIGECEYG IQHRKIRCII
     ELTSSQQINN HLQKSEDDSS LRLSINHLDS FLIRRSRSAN VMDVDHERCR NAGAKPISER
     PCLINLSCPY WYKSEWSKCS VNCGMGVRSR QVVCRSSNGT VINVETTDDK QVFYYNTETS
     HVNSLQYAIQ TIKKSATTRR KCLSPRPIDK VSCRTRPCTG LEVFWWPVTS SECNITGCEL
     TKRERIIKCI SPRRGPVHDA VCNHLEKPLN WTICELFKCK RFEWSTGSWS LCPDTCESRM
     RSRQVKCVDD LGNEYSETLC PASLKPSNRG VCPNLCAEVP KSCRELKYRY PSADDGTYQL
     LIEQSLVYIY CANMESSNPS EYITLRQINY AASSEFLQPF TSGSLSWKFE TNPIGDLYTE
     TQVCQAEEFQ YPDLKWCPSV NQNTSMFNIS TNIYQPNSNF DSSKDIPESL LTSMEVNNVN
     CPNCPTVSNL ASKTFYNKVR LDIYSLEVKS
//