ID A0A183NV23_9TREM Unreviewed; 371 AA.
AC A0A183NV23;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 25.
DE RecName: Full=Ectonucleoside triphosphate diphosphohydrolase 4 {ECO:0008006|Google:ProtNLM};
GN ORFNames=SMTD_LOCUS5959 {ECO:0000313|EMBL:VDP31278.1};
OS Schistosoma mattheei.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=31246 {ECO:0000313|WBParaSite:SMTD_0000595801-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:SMTD_0000595801-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDP31278.1, ECO:0000313|Proteomes:UP000269396}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Denwood {ECO:0000313|EMBL:VDP31278.1}, and Denwood, Zambia
RC {ECO:0000313|Proteomes:UP000269396};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the GDA1/CD39 NTPase family.
CC {ECO:0000256|ARBA:ARBA00009283}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; UZAL01027303; VDP31278.1; -; Genomic_DNA.
DR STRING; 31246.A0A183NV23; -.
DR WBParaSite; SMTD_0000595801-mRNA-1; SMTD_0000595801-mRNA-1; SMTD_0000595801.
DR Proteomes; UP000269396; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR Gene3D; 3.30.420.40; -; 1.
DR Gene3D; 3.30.420.150; Exopolyphosphatase. Domain 2; 1.
DR InterPro; IPR000407; GDA1_CD39_NTPase.
DR PANTHER; PTHR11782; ADENOSINE/GUANOSINE DIPHOSPHATASE; 1.
DR PANTHER; PTHR11782:SF121; NUCLEOSIDE-DIPHOSPHATASE MIG-23; 1.
DR Pfam; PF01150; GDA1_CD39; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW Nucleotide-binding {ECO:0000256|PIRSR:PIRSR600407-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000269396}.
FT ACT_SITE 121
FT /note="Proton acceptor"
FT /evidence="ECO:0000256|PIRSR:PIRSR600407-1"
FT BINDING 158..162
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PIRSR:PIRSR600407-2"
SQ SEQUENCE 371 AA; 41963 MW; 038664590097E5E6 CRC64;
MFVYTWQTKA ESLSGLEDVE ILKDVSGNPV VKKKTPGLSS FANKLSDIPD YISALLSDAE
SHIPLSSQPS TPLFIMATAG MRLLTQTDQD AIWKRVRSHV KSTYKFQFKE SHAYTISGVE
EGLFGWISVN YLLGKFRLLP GDNGPVKQPT NGMLDMGGAS MQIAYEVQST DNLPSSLVSE
FSLTRNWFST NQRYKLYVKS YLGYGMNAFR RKYEQYLFEM FGINNSSKQK ASRIEDPCLL
EGFNVISEIT PRPVIGEMLE PASEKFSVQF TGTGNMDKCM QNVEPLLNLN QSCSPLPCAI
NNVVQLDPDF NSVEFYGLSE FYYTLETLKM IPPVQYNYSS VLRKIEETCS TPWETYLSTL
RKENTNLSEE K
//
