ID A0A183P3C3_9TREM Unreviewed; 475 AA.
AC A0A183P3C3;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=GPR180/TMEM145 transmembrane domain-containing protein {ECO:0000259|Pfam:PF10192};
GN ORFNames=SMTD_LOCUS8860 {ECO:0000313|EMBL:VDP46840.1};
OS Schistosoma mattheei.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=31246 {ECO:0000313|WBParaSite:SMTD_0000885801-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:SMTD_0000885801-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDP46840.1, ECO:0000313|Proteomes:UP000269396}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Denwood {ECO:0000313|EMBL:VDP46840.1}, and Denwood, Zambia
RC {ECO:0000313|Proteomes:UP000269396};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; UZAL01029233; VDP46840.1; -; Genomic_DNA.
DR WBParaSite; SMTD_0000885801-mRNA-1; SMTD_0000885801-mRNA-1; SMTD_0000885801.
DR Proteomes; UP000269396; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0007186; P:G protein-coupled receptor signaling pathway; IEA:InterPro.
DR GO; GO:0019236; P:response to pheromone; IEA:InterPro.
DR InterPro; IPR047831; GPR180/TMEM145.
DR InterPro; IPR019336; GPR180/TMEM145_TM.
DR PANTHER; PTHR23252:SF45; GPCRRHOPSN4 DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR23252; INTIMAL THICKNESS RECEPTOR-RELATED; 1.
DR Pfam; PF10192; GpcrRhopsn4; 2.
PE 4: Predicted;
KW Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000269396};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 170..191
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 211..234
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 339..361
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 373..395
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 431..453
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 137..269
FT /note="GPR180/TMEM145 transmembrane"
FT /evidence="ECO:0000259|Pfam:PF10192"
FT DOMAIN 333..395
FT /note="GPR180/TMEM145 transmembrane"
FT /evidence="ECO:0000259|Pfam:PF10192"
SQ SEQUENCE 475 AA; 54047 MW; 1D5B3D9FBDFA9DF8 CRC64;
MDLYGNATES IWTQNVTGTT YQESQWLIET ERCNKMFDKI NSLAWHKTCS PTGEMDLLRS
VPCSSSGLCA EEDDPESVVP NSQFTFIVQD LRQPRYWYLS LVACKRNLTT CKWETTAIPR
HSNSSLSSSL TYSLLTVIYD IWLVNGEPKL QSFNQFEHHF SFETHGIAQM FFIFLSLYII
LNITTHVRFN WPFIIYHYVQ IKLANNRSLH VCLYLTHLWL ASLGTLLAAV HWGVFSFDGL
GLGLISELGT VITQWADSVF LAVLLCTCQM GFSPQCPSIA FQSCDTSKAL RPPTSKVFST
LPTGFLHLGK FSHKLYSYDP IQEKIYARPS TNQEKSTSFW PYVILLVTLL VGVKTLLYIW
AMFDRDPVID FSVWNTVPGC LLLALRICLV FWILVVVGRR HFIAQICSES YNMDLCILGP
NINTMQFAAG YLLWIVILPL VVFIGETSVS PLWRTKTISS KYLSGELNFL VGKVI
//
