ID   A0A183P4L2_9TREM        Unreviewed;       928 AA.
AC   A0A183P4L2;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 25.
DE   SubName: Full=Importin N-terminal domain-containing protein {ECO:0000313|WBParaSite:SMTD_0000929701-mRNA-1};
GN   ORFNames=SMTD_LOCUS9298 {ECO:0000313|EMBL:VDP49142.1};
OS   Schistosoma mattheei.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=31246 {ECO:0000313|WBParaSite:SMTD_0000929701-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SMTD_0000929701-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDP49142.1, ECO:0000313|Proteomes:UP000269396}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Denwood {ECO:0000313|EMBL:VDP49142.1}, and Denwood, Zambia
RC   {ECO:0000313|Proteomes:UP000269396};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the exportin family.
CC       {ECO:0000256|ARBA:ARBA00009466}.
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DR   EMBL; UZAL01029589; VDP49142.1; -; Genomic_DNA.
DR   STRING; 31246.A0A183P4L2; -.
DR   WBParaSite; SMTD_0000929701-mRNA-1; SMTD_0000929701-mRNA-1; SMTD_0000929701.
DR   Proteomes; UP000269396; Unassembled WGS sequence.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-KW.
DR   GO; GO:0005049; F:nuclear export signal receptor activity; IEA:InterPro.
DR   GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR   GO; GO:0006611; P:protein export from nucleus; IEA:InterPro.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR041123; CRM1_repeat.
DR   InterPro; IPR041235; Exp1_repeat_2.
DR   InterPro; IPR013598; Exportin-1/Importin-b-like.
DR   InterPro; IPR001494; Importin-beta_N.
DR   InterPro; IPR045065; XPO1/5.
DR   InterPro; IPR014877; XPO1_C_dom.
DR   InterPro; IPR040485; XPO1_repeat_3.
DR   PANTHER; PTHR11223; EXPORTIN 1/5; 1.
DR   PANTHER; PTHR11223:SF2; EXPORTIN-1; 1.
DR   Pfam; PF08767; CRM1_C; 1.
DR   Pfam; PF18777; CRM1_repeat; 1.
DR   Pfam; PF18784; CRM1_repeat_2; 1.
DR   Pfam; PF18787; CRM1_repeat_3; 1.
DR   Pfam; PF03810; IBN_N; 1.
DR   Pfam; PF08389; Xpo1; 1.
DR   SMART; SM01102; CRM1_C; 1.
DR   SMART; SM00913; IBN_N; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
DR   PROSITE; PS50166; IMPORTIN_B_NT; 1.
PE   3: Inferred from homology;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW   Reference proteome {ECO:0000313|Proteomes:UP000269396};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          157..203
FT                   /note="Importin N-terminal"
FT                   /evidence="ECO:0000259|PROSITE:PS50166"
SQ   SEQUENCE   928 AA;  107017 MW;  B791890E7A603A7B CRC64;
     MLNEFRITTE SFSGQDSDFI VQRTVDTACI IYDACVSIRL TCPSSARHCC MAITISFNSC
     EFFTGYLDSC MYQVVRPFDS RLYVNCDQTG AGVKVPRNYF ILVLVTTRYM PPTSPMGVIS
     ESAAAQLLDF SQRLDIGLLD RVVNCMYHEA GDQQKIAEKV LNTLKEHPDA WMRVDSILEF
     SSNQETKYFA LQILEALIKT RWKVLARPQC EVHRWFDNPN IVQFGALGVG KDVSRQILKH
     EWPNNWSTFI SDIVGASKTN ESLCQNNMVI LRLLSEEVFD FSLGQMTQTK AKHLKDSMCQ
     QFSLIFQLCQ YVLENSQNAS LVVSTLETLL RFMHWIPLGY IFETNLIQTL VFKFFNVPLF
     RNITLKCLAE IETRLKEAYE RGSNDEQNFI QNLAIFYTTF LKGHSSLVEK PELIWKLQDA
     YAYLLMLSEV EEREIFKICL EYWNILVSDL YRESLTTTVV GTLAESTTGE GRSKQYAPIL
     SKLRRIMISR MARPEEVLVV ENEHGEVVRE FMKDTDSLNL YKSMRETLVY LTHLDYSDTK
     KIMIEKLQHQ VDGREWSWHN LNTLCWAIGS ISGAMQEDDE RSFLVIVIRD LLGLCEQKRG
     KDNKAIVASN IMYVVGQYPR FLRAHWRFLK TVITKLFEFM HETHEGVQDM ACDTFIKIAQ
     KCRRQLVTVQ IWDGILVQAA CNIDLLRDFE VVQQLCNLLK TNHSACKSLG HSYLVQLGRI
     YLDMLNVYKI MSQNIGQAVA TNGEQVTKQP LIRSMRSVKK AILNLLSCWI KRTTDPVFVA
     ENILPPLLDA VADDYQKNLP AAREAEVLSL MATLVNRLED HILPALPRVL DAVFQSTLEM
     IDKDLEEFPE HRTNFFTLLQ AVNAHCFSAL LSLTSDKFKL ILDSVIWAIK HTMRQVSSHT
     FHFYFDSFNI TLWVSNNTKV FMFLRIFL
//