ID A0A183PUG1_9TREM Unreviewed; 135 AA.
AC A0A183PUG1;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE RecName: Full=UDP-glucose--hexose-1-phosphate uridylyltransferase {ECO:0000256|ARBA:ARBA00012384};
DE EC=2.7.7.12 {ECO:0000256|ARBA:ARBA00012384};
DE AltName: Full=UDP-glucose--hexose-1-phosphate uridylyltransferase {ECO:0000256|ARBA:ARBA00030549};
GN ORFNames=SMTD_LOCUS17997 {ECO:0000313|EMBL:VDP75853.1};
OS Schistosoma mattheei.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=31246 {ECO:0000313|WBParaSite:SMTD_0001799601-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:SMTD_0001799601-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDP75853.1, ECO:0000313|Proteomes:UP000269396}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Denwood {ECO:0000313|EMBL:VDP75853.1}, and Denwood, Zambia
RC {ECO:0000313|Proteomes:UP000269396};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-
CC glucose 1-phosphate + UDP-alpha-D-galactose; Xref=Rhea:RHEA:13989,
CC ChEBI:CHEBI:58336, ChEBI:CHEBI:58601, ChEBI:CHEBI:58885,
CC ChEBI:CHEBI:66914; EC=2.7.7.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001107};
CC -!- PATHWAY: Carbohydrate metabolism; galactose metabolism.
CC {ECO:0000256|ARBA:ARBA00004947}.
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DR EMBL; UZAL01039677; VDP75853.1; -; Genomic_DNA.
DR STRING; 31246.A0A183PUG1; -.
DR WBParaSite; SMTD_0001799601-mRNA-1; SMTD_0001799601-mRNA-1; SMTD_0001799601.
DR Proteomes; UP000269396; Unassembled WGS sequence.
DR GO; GO:0008108; F:UDP-glucose:hexose-1-phosphate uridylyltransferase activity; IEA:UniProtKB-EC.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0033499; P:galactose catabolic process via UDP-galactose; IEA:InterPro.
DR Gene3D; 3.30.428.10; HIT-like; 1.
DR InterPro; IPR001937; GalP_UDPtransf1.
DR InterPro; IPR019779; GalP_UDPtransf1_His-AS.
DR InterPro; IPR005849; GalP_Utransf_N.
DR InterPro; IPR036265; HIT-like_sf.
DR PANTHER; PTHR11943; GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR PANTHER; PTHR11943:SF1; GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE; 1.
DR Pfam; PF01087; GalP_UDP_transf; 1.
DR SUPFAM; SSF54197; HIT-like; 1.
DR PROSITE; PS00117; GAL_P_UDP_TRANSF_I; 1.
PE 4: Predicted;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Nucleotidyltransferase {ECO:0000256|ARBA:ARBA00022695};
KW Reference proteome {ECO:0000313|Proteomes:UP000269396};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 17..99
FT /note="Galactose-1-phosphate uridyl transferase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF01087"
SQ SEQUENCE 135 AA; 15376 MW; 9CFC503B16E488A6 CRC64;
VNVNCECESV SLTSFRSVEE NPLFACAPAQ GDCLVTCFHP DSNKTLALME QREILSVITE
WCRITEKYFK MKKFQWLQIF ENRGAAVGSS NTHPHCQLIT SFLIQLVSSV THPKYHRLTL
SNQTDSPNCT FRPSF
//
