ID A0A183QD25_9TREM Unreviewed; 328 AA.
AC A0A183QD25;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 21.
DE RecName: Full=DNA damage-binding protein 1 {ECO:0000256|ARBA:ARBA00014577, ECO:0000256|RuleBase:RU368023};
DE AltName: Full=Damage-specific DNA-binding protein 1 {ECO:0000256|RuleBase:RU368023};
OS Schistosoma rodhaini.
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX NCBI_TaxID=6188 {ECO:0000313|WBParaSite:SROB_0000152801-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:SROB_0000152801-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
CC -!- FUNCTION: Component of complexes involved in DNA repair and protein
CC ubiquitination. May play a role in the regulation of the circadian
CC clock. {ECO:0000256|RuleBase:RU368023}.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC {ECO:0000256|RuleBase:RU368023}.
CC -!- SUBUNIT: Component of the UV-DDB complex.
CC {ECO:0000256|RuleBase:RU368023}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU368023}.
CC -!- DOMAIN: The core of the protein consists of three WD40 beta-propeller
CC domains. {ECO:0000256|RuleBase:RU368023}.
CC -!- SIMILARITY: Belongs to the DDB1 family.
CC {ECO:0000256|RuleBase:RU368023}.
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DR AlphaFoldDB; A0A183QD25; -.
DR STRING; 6188.A0A183QD25; -.
DR WBParaSite; SROB_0000152801-mRNA-1; SROB_0000152801-mRNA-1; SROB_0000152801.
DR UniPathway; UPA00143; -.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
DR GO; GO:0043161; P:proteasome-mediated ubiquitin-dependent protein catabolic process; IEA:UniProtKB-UniRule.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniRule.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR018846; Cleavage/polyA-sp_fac_asu_N.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR PANTHER; PTHR10644:SF3; DNA DAMAGE-BINDING PROTEIN 1; 1.
DR PANTHER; PTHR10644; DNA REPAIR/RNA PROCESSING CPSF FAMILY; 1.
DR Pfam; PF10433; MMS1_N; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|RuleBase:RU368023};
KW DNA repair {ECO:0000256|RuleBase:RU368023};
KW Nucleus {ECO:0000256|RuleBase:RU368023}.
FT DOMAIN 75..298
FT /note="Cleavage/polyadenylation specificity factor A
FT subunit N-terminal"
FT /evidence="ECO:0000259|Pfam:PF10433"
SQ SEQUENCE 328 AA; 36503 MW; 13BEA96B62EA9C8F CRC64;
MAHFYHVTTQ RPTAVVKTCT GHFTSPNDLN LLICKNTYVE VFEVTCEGLK LIRDVPINAK
IVAASLFRRK DRETDSLFLL THKAGVAIIE CVRNNDSVEF VTVASGSVED RSARIIDQGF
DVLIDPGANY IVVRLYHGLL KIILLQCIGE KIGTDFIDTN QWTIISLRIE EGNIVDMAFI
YGYSLPTFAM IYEDELVLHM KTYEIYGREP VLRNVQLTLD SIEPDSKLLI PVPKPYGGVI
LVGDNIICYH TKDGPHISQY IPQAKASQVL CYAAVDAQRY LLGDMAGRLY MVHLLSEDIS
AATNNGTSNS DSLSAVRIGS IRIELLGM
//
