ID   A0A183R3Q5_9TREM        Unreviewed;       991 AA.
AC   A0A183R3Q5;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=Dynein heavy chain AAA module D4 domain-containing protein {ECO:0008006|Google:ProtNLM};
OS   Schistosoma rodhaini.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6188 {ECO:0000313|WBParaSite:SROB_0001059501-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SROB_0001059501-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the dynein heavy chain family.
CC       {ECO:0000256|ARBA:ARBA00008887}.
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DR   AlphaFoldDB; A0A183R3Q5; -.
DR   STRING; 6188.A0A183R3Q5; -.
DR   WBParaSite; SROB_0001059501-mRNA-1; SROB_0001059501-mRNA-1; SROB_0001059501.
DR   GO; GO:0030286; C:dynein complex; IEA:InterPro.
DR   GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR   GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR   GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR   GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR   Gene3D; 1.20.920.20; -; 1.
DR   Gene3D; 1.20.920.30; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR035706; AAA_9.
DR   InterPro; IPR026983; DHC_fam.
DR   InterPro; IPR041589; DNAH3_AAA_lid_1.
DR   InterPro; IPR024743; Dynein_HC_stalk.
DR   InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   PANTHER; PTHR10676:SF343; DYNEIN AXONEMAL HEAVY CHAIN 10; 1.
DR   PANTHER; PTHR10676; DYNEIN HEAVY CHAIN FAMILY PROTEIN; 1.
DR   Pfam; PF12775; AAA_7; 1.
DR   Pfam; PF12780; AAA_8; 1.
DR   Pfam; PF12781; AAA_9; 1.
DR   Pfam; PF17857; AAA_lid_1; 1.
DR   Pfam; PF12777; MT; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils}.
FT   DOMAIN          107..197
FT                   /note="Dynein heavy chain 3 AAA+ lid"
FT                   /evidence="ECO:0000259|Pfam:PF17857"
FT   DOMAIN          250..510
FT                   /note="Dynein heavy chain AAA module D4"
FT                   /evidence="ECO:0000259|Pfam:PF12780"
FT   DOMAIN          524..850
FT                   /note="Dynein heavy chain coiled coil stalk"
FT                   /evidence="ECO:0000259|Pfam:PF12777"
FT   DOMAIN          876..974
FT                   /note="Dynein heavy chain ATP-binding dynein motor region"
FT                   /evidence="ECO:0000259|Pfam:PF12781"
FT   COILED          525..552
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          730..785
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   991 AA;  114288 MW;  EBA490B7DB0CC3E4 CRC64;
     MNMPQVDQYG TQQPIALLKL LIERKGVYDR GKELNWKRMQ SIDYLAAMGC PDGGKQDVDP
     RFISLFSVIN IQSPSESTLY KIYSSILTGH TSEFDSGIKN SVNSVTNMTL KLFQFVSVQL
     PPTPSRFHYV FNMRDHSRIF NGLCLMTIDK FSRKEQCIRL WLHEVYRVVM DRLISHDDKQ
     LVEKYIDELL QENSKEIKEY VTKMPILFGD YRNAMDESEI RLYEDMIDYE NCRTIAQEIL
     DNYNESIGQL QMILFNDAIE HFTRIERVLR MENGHALLVG VGGSGKQSLT RLAAYASNST
     LFEIQLCRGY GEREFREELK TLYLRLGIEN KSTVFMFTDQ HVVEEGFLEL INNMLTTGSV
     PALFGDDERE SITGQLRDEA VAIGCPPTRE SIWQYFIQKA ASNLHIVLCM SPVGDTLRTR
     CRNFPGIVNN TTIDWFFPWP EQALYAVVNV LIPEQFNLVP QQYRDSVIDY FVATHQSIHG
     YTIEFAQTLR RVNHVTPKHY LDFIHTYKRL ITEKDNDNEK QIIRLQSGLQ KLAEASIQLE
     ELNAKLAVQR VAVTEKTQAC ENLLNEITNS SQLAIEKKEL AVLKSKEIQI QSVEIEQEKV
     RFVYFINLQA LDDLDKSDVT EIRSFAKPPK AVQVVSECIC VFKGYKEISW KTAKGMMSDT
     NFLQSLQTMD VDNITSKQSS TVKDYLDKSK VTMDEMKSVS KAGTGLLKFV VAVLGYSEVA
     RDIKPKRDKV AKLEKTFMQA KRDLTRINAE LSNLESELIS LNRRYEEAMS ERLKLQEETD
     IMERRLIAAD KLITGLSSEE IRWLKDLDGL KIKRVKLLGD CLISAAFLSY VGAFSSEFRT
     RMIYEDWQRW LQERQIPLSD QFRLEDILTS DVEVSRWNSE GLPPDELSIQ NGILTVQSSR
     FPLCIDPQEQ ALHWICHKEE ANNLKIATFN DSDFLKQLEL SIRYGIPFLF KDVDDYIDPV
     INNVLEKNIK GDQVSQYLFP LLKISMKFSS I
//