ID   A0A183RF75_9TREM        Unreviewed;       251 AA.
AC   A0A183RF75;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   RecName: Full=sphingosine kinase {ECO:0000256|ARBA:ARBA00044037};
DE            EC=2.7.1.91 {ECO:0000256|ARBA:ARBA00044037};
OS   Schistosoma rodhaini.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6188 {ECO:0000313|WBParaSite:SROB_0001465701-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SROB_0001465701-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a sphingoid base + ATP = a sphingoid 1-phosphate + ADP + H(+);
CC         Xref=Rhea:RHEA:51496, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC         ChEBI:CHEBI:76941, ChEBI:CHEBI:84410, ChEBI:CHEBI:456216;
CC         EC=2.7.1.91; Evidence={ECO:0000256|ARBA:ARBA00043822};
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DR   AlphaFoldDB; A0A183RF75; -.
DR   STRING; 6188.A0A183RF75; -.
DR   WBParaSite; SROB_0001465701-mRNA-1; SROB_0001465701-mRNA-1; SROB_0001465701.
DR   GO; GO:0016301; F:kinase activity; IEA:InterPro.
DR   Gene3D; 2.60.200.40; -; 1.
DR   InterPro; IPR017438; ATP-NAD_kinase_N.
DR   InterPro; IPR001206; Diacylglycerol_kinase_cat_dom.
DR   InterPro; IPR016064; NAD/diacylglycerol_kinase_sf.
DR   PANTHER; PTHR12358:SF31; LD11247P-RELATED; 1.
DR   PANTHER; PTHR12358; SPHINGOSINE KINASE; 1.
DR   Pfam; PF00781; DAGK_cat; 1.
DR   SUPFAM; SSF111331; NAD kinase/diacylglycerol kinase-like; 1.
DR   PROSITE; PS50146; DAGK; 1.
PE   4: Predicted;
FT   DOMAIN          1..78
FT                   /note="DAGKc"
FT                   /evidence="ECO:0000259|PROSITE:PS50146"
FT   REGION          215..251
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   251 AA;  28693 MW;  D81E23303240D841 CRC64;
     MPHFCCLEYP GHAENFIINL PKANLLRYRA IVTCSGDGLV YEVINGLISR KDYDDVIEED
     TIPIGILPGG SANSTAASIC YHSGLLGKSS LLSHCGFLLT LPIENIQNKQ YQQVNEQNEK
     YSCTLPVLPR ITPVSCIHFG TCDTNFHRYG IQSIEWGFIA DLDYKSERFR WMGEKRFLLY
     ACYYLMKKPT YRAKLSYLPI DNVLYQKNKY KNDELVQKSS ESSTECENSS DLTDKLNESP
     KQIKKSHQSW S
//