ID   A0A183RV76_9TREM        Unreviewed;       542 AA.
AC   A0A183RV76;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   SubName: Full=HMG box domain-containing protein {ECO:0000313|WBParaSite:SROB_0001994501-mRNA-1};
OS   Schistosoma rodhaini.
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma.
OX   NCBI_TaxID=6188 {ECO:0000313|WBParaSite:SROB_0001994501-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SROB_0001994501-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC   -!- SIMILARITY: Belongs to the TCF/LEF family.
CC       {ECO:0000256|ARBA:ARBA00006569}.
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DR   AlphaFoldDB; A0A183RV76; -.
DR   STRING; 6188.A0A183RV76; -.
DR   WBParaSite; SROB_0001994501-mRNA-1; SROB_0001994501-mRNA-1; SROB_0001994501.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-UniRule.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0016055; P:Wnt signaling pathway; IEA:UniProtKB-KW.
DR   CDD; cd21996; HMG-box_TCF7-like; 1.
DR   Gene3D; 1.10.30.10; High mobility group box domain; 1.
DR   InterPro; IPR009071; HMG_box_dom.
DR   InterPro; IPR036910; HMG_box_dom_sf.
DR   InterPro; IPR024940; TCF/LEF.
DR   PANTHER; PTHR10373:SF38; PROTEIN PANGOLIN, ISOFORM J; 1.
DR   PANTHER; PTHR10373; TRANSCRIPTION FACTOR 7 FAMILY MEMBER; 1.
DR   Pfam; PF00505; HMG_box; 1.
DR   SMART; SM00398; HMG; 1.
DR   SUPFAM; SSF47095; HMG-box; 1.
DR   PROSITE; PS50118; HMG_BOX_2; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU00267}; Nucleus {ECO:0000256|PROSITE-ProRule:PRU00267};
KW   Wnt signaling pathway {ECO:0000256|ARBA:ARBA00022687}.
FT   DOMAIN          477..542
FT                   /note="HMG box"
FT                   /evidence="ECO:0000259|PROSITE:PS50118"
FT   DNA_BIND        477..542
FT                   /note="HMG box"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00267"
FT   REGION          275..295
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          442..474
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   542 AA;  58293 MW;  09EBF8BF5262B684 CRC64;
     MFPSFGGLSP SLSAFMAGPF YSVALQAAAV AAAVSSGSSS PKLQSTSWPQ PSVHSPVPFR
     IPTPNTSLSN LNVYDNLSSQ NKSSPSVIAV AAAAAAAAAL SQSPSSTSAT AAAAFHSELI
     KAANLYKINN NSNQRFLPNP NPCHHSLSHD NLLSLCTNSS NQSSSSTLPL NIDNSMNIYN
     TASDNMTIGG SVHPSNKSTS TNLPSRLYPL TGSKLDQYSS SINLQLKTDN DNFTDKHFTE
     FSSLDNSSNK SIHSERLVIP SNSFGEQAAS YDLQRKLGSS TSTRTTDLSV KSDSEENQLN
     RSLFTDCSQR ATAAAAAAAA AAAHVQFLSS LAVAAAVHSS ASSSSPTPVP QLSSLHNSSS
     LSPILSRNNS VDSNLQHSIS SHLDIVQSSS VSTSQEPLFS FTTSQLKSRH TNTTDNFAHQ
     ISGHLKAFKS FGSTTDNVCS SSHNTNYNHN KDHCNQPHQQ QQQPPISNTN STKRVHIKKP
     LNAFMLFMKD MRPIVQEECT LKESAAINQI LGKKWHELSR DKQAKYYELA RKEKELHHQV
     DK
//