ID A0A183SDX2_SCHSO Unreviewed; 923 AA.
AC A0A183SDX2;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=SSLN_LOCUS2420 {ECO:0000313|EMBL:VDL88805.1};
OS Schistocephalus solidus (Tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Diphyllobothriidea; Diphyllobothriidae; Schistocephalus.
OX NCBI_TaxID=70667 {ECO:0000313|Proteomes:UP000050788, ECO:0000313|WBParaSite:SSLN_0000249401-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:SSLN_0000249401-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDL88805.1, ECO:0000313|Proteomes:UP000275846}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NST_G2 {ECO:0000313|EMBL:VDL88805.1,
RC ECO:0000313|Proteomes:UP000275846};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
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DR EMBL; UYSU01032246; VDL88805.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A183SDX2; -.
DR STRING; 70667.A0A183SDX2; -.
DR WBParaSite; SSLN_0000249401-mRNA-1; SSLN_0000249401-mRNA-1; SSLN_0000249401.
DR Proteomes; UP000050788; Unplaced.
DR Proteomes; UP000275846; Unassembled WGS sequence.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR Gene3D; 1.10.3380.10; Sec63 N-terminal domain-like domain; 1.
DR InterPro; IPR004179; Sec63-dom.
DR PANTHER; PTHR47835; HFM1, ATP DEPENDENT DNA HELICASE HOMOLOG; 1.
DR PANTHER; PTHR47835:SF2; SEC63 DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF02889; Sec63; 1.
DR SMART; SM00973; Sec63; 1.
DR SUPFAM; SSF158702; Sec63 N-terminal domain-like; 1.
PE 4: Predicted;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Reference proteome {ECO:0000313|Proteomes:UP000275846}.
FT DOMAIN 1..324
FT /note="SEC63"
FT /evidence="ECO:0000259|SMART:SM00973"
FT REGION 391..410
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 795..827
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 923 AA; 101980 MW; D5CB12C56B555947 CRC64;
MSEHFLGYST VASFLQLSGY EKMNELISFV AKCREFGDIS LRQQEKYLLN RLNKSSGLQK
LRYPVPGSVS SPEAKISILL QAQLNDHILL DSTIQADANK IMICFIRTVI GLRSIVLLDE
EQIQRTVKTF DENSLIEEFE ERMEKNGFSC LIDIVELCKA VFYKLWPDHP LASIRQLPGI
GKDFADRLAS AGITSIAGIE KSGPRKIEEV LSRVRPFGDN IYEAALKVPK YELAVEQVLT
NTPEVLSFNF VIRLVRSCGF DQAAFIVGDD KNRILLKRKI TTSEIEAAGE WSQVVSIQRK
SESLRLFVSL LSLNFCGPDD VMDCASLGMN FRGSRPYQLN PFLSSTTEAA NRRSKNNFHV
LTNCFKPGLG LTPSSTSPIG YRSRIKGSNT KLVRNHSRPP QNPSSFQYGT DSSFNKIKTP
LIQTKIQNFF RKTKSFSEET PLHPSTDNKV PVKSSAELIT PQTTLFRPPH SCEAKIHGLL
GPDHPPQPVK RFKWDPRKVK HSTPNEKARG ALLGSPTSEQ VGKAVMNRTF GALLSSPPPL
SSDGMERQPP LHTPFNLCYS ADKIAHSTAT LELSPRLALD ISPIRPLDTE EGTELSTIEN
SESQHVSTPV ASIKLTDMHS ERQLSCSFAE PFPVKDCKEP GLNTLTLADS HKATHNCSGL
EAVDSNNTYQ SPPFAELKED FLCHRGSTNA NFAADIRSDG ERRHSLIVNC HTSLDNSVAS
NSPHRPSTVD LDNFPVASCS RLPINTPTDQ GKFSKKVSFG SLCNLRALTP GAKNPKTTDI
DVGYGSEPMI SLLQTKPSMP CPTSEIEETK NPKPGTSHSE TTRKPMMAAR STDSDCLEEN
QLTTRDFDLI CSGWEELATF ICCYNILKDL SCDESLFVTM SAPRTPPPTP TYGDSVHGHS
CLTVDSINTQ VPCLSAAVNL SFN
//
