ID   A0A183SJF1_SCHSO        Unreviewed;      1004 AA.
AC   A0A183SJF1;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Lig_chan-Glu_bd domain-containing protein {ECO:0000313|WBParaSite:SSLN_0000449601-mRNA-1};
GN   ORFNames=SSLN_LOCUS4349 {ECO:0000313|EMBL:VDL90734.1};
OS   Schistocephalus solidus (Tapeworm).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC   Eucestoda; Diphyllobothriidea; Diphyllobothriidae; Schistocephalus.
OX   NCBI_TaxID=70667 {ECO:0000313|Proteomes:UP000050788, ECO:0000313|WBParaSite:SSLN_0000449601-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SSLN_0000449601-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDL90734.1, ECO:0000313|Proteomes:UP000275846}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NST_G2 {ECO:0000313|EMBL:VDL90734.1,
RC   ECO:0000313|Proteomes:UP000275846};
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; UYSU01032834; VDL90734.1; -; Genomic_DNA.
DR   STRING; 70667.A0A183SJF1; -.
DR   WBParaSite; SSLN_0000449601-mRNA-1; SSLN_0000449601-mRNA-1; SSLN_0000449601.
DR   Proteomes; UP000050788; Unplaced.
DR   Proteomes; UP000275846; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015276; F:ligand-gated monoatomic ion channel activity; IEA:InterPro.
DR   GO; GO:0038023; F:signaling receptor activity; IEA:InterPro.
DR   GO; GO:0050906; P:detection of stimulus involved in sensory perception; IEA:UniProt.
DR   Gene3D; 1.10.287.70; -; 1.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 3.
DR   InterPro; IPR019594; Glu/Gly-bd.
DR   InterPro; IPR001508; Iono_Glu_rcpt_met.
DR   InterPro; IPR015683; Ionotropic_Glu_rcpt.
DR   InterPro; IPR001320; Iontro_rcpt_C.
DR   PANTHER; PTHR18966; IONOTROPIC GLUTAMATE RECEPTOR; 1.
DR   PANTHER; PTHR18966:SF422; KAINATE-TYPE IONOTROPIC GLUTAMATE RECEPTOR SUBUNIT 1D; 1.
DR   Pfam; PF00060; Lig_chan; 1.
DR   Pfam; PF10613; Lig_chan-Glu_bd; 1.
DR   PRINTS; PR00177; NMDARECEPTOR.
DR   SMART; SM00918; Lig_chan-Glu_bd; 1.
DR   SMART; SM00079; PBPe; 1.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Glycoprotein {ECO:0000256|ARBA:ARBA00023180};
KW   Ion channel {ECO:0000256|ARBA:ARBA00023303};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Ligand-gated ion channel {ECO:0000256|ARBA:ARBA00023286};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136};
KW   Receptor {ECO:0000256|ARBA:ARBA00023170};
KW   Reference proteome {ECO:0000313|Proteomes:UP000275846};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989};
KW   Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          559..936
FT                   /note="Ionotropic glutamate receptor C-terminal"
FT                   /evidence="ECO:0000259|SMART:SM00079"
FT   DOMAIN          576..630
FT                   /note="Ionotropic glutamate receptor L-glutamate and
FT                   glycine-binding"
FT                   /evidence="ECO:0000259|SMART:SM00918"
SQ   SEQUENCE   1004 AA;  112510 MW;  124565E81779F618 CRC64;
     MVFFERGKVI KIGVGFHFRQ SVDGCVRGSG GPVKKASEVL RPALQDFCLL SEQGRSVSTE
     KRVDSFDWTS VDSLNCDEEV LAFVAIHVPL DLLLLSEQGR SVSTEKRVDS FDWKSIDSLN
     CDEEVLAFVA IHVPLDLLGL VDNLGGLHLP LAISVEDGGF GSRLSCLQRE QSIDGCIVVI
     EPVFTLSKCT ANVILRGGLD RVPQLAQAVL HGGVLIGDWK TKPHLGDDEA MIRSSVGTGD
     QLSHQHVLLV SLPEEDIIQQ VSMSRPGVHS GPLLPYWDQV VFCEGADYGG EFLYPKRQAE
     AHLAIIAALR QTGQTFHDVF PDVIIDSWNH RKPTDPRGGI PVVTFRRNSS SDNGPQNRRS
     TAFDLAHVFS VWSANKIPQT VFLHTMSPDV EDIVAEAYDA GLISQNTFWT IMDEAGSNMN
     VSNLITKLNV ANDETLNPIK ARQRSRPNLA FIRRYPVLRN EDCFDSKLPL DLRSRMRRLF
     DCRVDHIPWY NETGLLNSLW MFASKTRKLH EPIKFYRTAQ LQRDGDFKMT DFGALMAPNS
     DISGLFPNAF YSFFGEGLRI GCLQAKGFVE GGYLDESGFL RNASGFQIDL LQLLQEQFEF
     SYELVIPADG EYGRRLSNGS WTGLIGLVVR RKVEFAVGPI TISALRAKAT QFMGPFQSAH
     LTAFYRTPAE SSNLVRMATP FHWQTWMLII SSIFLSSGLI CCLSRFSPYS AWNLRLSGAI
     SDEISIWDNL WNVFEGFVMQ AQDFYPFAYS SRILMASWWM YVVLVQAAYQ AELVAFLSRS
     EIMSPFETLE ELADDTTITP LIARASNTYY GCYTTSGHQG HQLCCEPQRP ISFKKASPES
     TYARLWKRTQ LVSEAEGMEK ILASPEFVYI DDEITAGAIE NAANRRISKL KKTFAHSFYG
     FPIVTGTEYM RAFDSYIHRL RETGIIQRLY SKWLQAPERP FGTAATGASM SIDMSQSSGT
     FILLGISALV SLLSLGMENL WSYNFPTLKV KWDDWKNRQS GAQS
//