ID A0A183STQ1_SCHSO Unreviewed; 2901 AA.
AC A0A183STQ1;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 24-JAN-2024, entry version 27.
DE RecName: Full=Nipped-B protein {ECO:0000256|RuleBase:RU364107};
GN ORFNames=SSLN_LOCUS7599 {ECO:0000313|EMBL:VDL93984.1};
OS Schistocephalus solidus (Tapeworm).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC Eucestoda; Diphyllobothriidea; Diphyllobothriidae; Schistocephalus.
OX NCBI_TaxID=70667 {ECO:0000313|Proteomes:UP000050788, ECO:0000313|WBParaSite:SSLN_0000788101-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:SSLN_0000788101-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDL93984.1, ECO:0000313|Proteomes:UP000275846}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=NST_G2 {ECO:0000313|EMBL:VDL93984.1,
RC ECO:0000313|Proteomes:UP000275846};
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|RuleBase:RU364107}.
CC -!- SIMILARITY: Belongs to the SCC2/Nipped-B family.
CC {ECO:0000256|ARBA:ARBA00009252, ECO:0000256|RuleBase:RU364107}.
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DR EMBL; UYSU01034220; VDL93984.1; -; Genomic_DNA.
DR STRING; 70667.A0A183STQ1; -.
DR WBParaSite; SSLN_0000788101-mRNA-1; SSLN_0000788101-mRNA-1; SSLN_0000788101.
DR Proteomes; UP000050788; Unplaced.
DR Proteomes; UP000275846; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003682; F:chromatin binding; IEA:InterPro.
DR GO; GO:0009790; P:embryo development; IEA:UniProt.
DR GO; GO:0061780; P:mitotic cohesin loading; IEA:InterPro.
DR GO; GO:0010468; P:regulation of gene expression; IEA:InterPro.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR026003; Cohesin_HEAT.
DR InterPro; IPR024986; Nipped-B_C.
DR InterPro; IPR033031; Scc2/Nipped-B.
DR PANTHER; PTHR21704:SF18; NIPPED-B-LIKE PROTEIN; 1.
DR PANTHER; PTHR21704; NIPPED-B-LIKE PROTEIN DELANGIN SCC2-RELATED; 1.
DR Pfam; PF12765; Cohesin_HEAT; 1.
DR Pfam; PF12830; Nipped-B_C; 1.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 3: Inferred from homology;
KW Cell cycle {ECO:0000256|ARBA:ARBA00023306, ECO:0000256|RuleBase:RU364107};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|RuleBase:RU364107};
KW Reference proteome {ECO:0000313|Proteomes:UP000275846};
KW Repeat {ECO:0000256|ARBA:ARBA00022737, ECO:0000256|RuleBase:RU364107}.
FT DOMAIN 2238..2507
FT /note="Sister chromatid cohesion C-terminal"
FT /evidence="ECO:0000259|Pfam:PF12830"
FT REGION 118..183
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 215..258
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 530..577
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 629..753
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1383..1505
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1560..1603
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2344..2415
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2562..2586
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2786..2901
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 118..137
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 157..183
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 530..561
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 651..673
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 732..753
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1397..1461
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2358..2407
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 2887..2901
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2901 AA; 318884 MW; B653F0BF4EC44BA3 CRC64;
MNGDISRIPI QSLGAVFSLT DILPELPLPS ALPHGPGNDT FLSDSVLSND AVRCLLSKDE
TLTSILAEAL TNVSTDNITF LSDLNDNPST EALDSSNLPP LLVSVLQKND SVFHRKRGSY
LESQKKHALD EISESPSKKK HKKKKHKRRK SDHNDNNASS GVDSAAATPA GSSCGARSTS
EDVISSATPQ VPYGVSVNVN PDEKKILLKF SFKRPPTDDS TCNHVQSTES KAKKEKKTKR
SKDHDCKRHR SLESKQPKVS AGYLFESKPN QGLPFSKPTC DPIDPFEMSP QLVLSANGTA
PMPTKLISNV PSNFTSSEQL DHKTSLPPPS TLSPNSMLEG IAAISSSSSH PADLRMVFDT
SIINSSSSRM DYASPDLFLN DLAVSHAFNS STSHPVAPAP PNFSVMDYDN YIPTDLLGMT
ANLAPSVSSG PLFSGETGQA SNCSPSQESK VYRGSFMVAS HLDYDLKRPT QDQALFLDNI
PTSTSVPEFH NSALHMSTPQ KVSSSHLKGY DIASLADPMS QVTPMGLASY LNSSQQNPKS
TPSMQSPNNA HLHSTSKAVN ASGKPPRRRP IVSRRRRRNE LEDLRSWAVK YPSGTPTSAS
LKPNAVDRLS DETSSWDATV GSYSQALGER AKRRKRMANH PSALTSDFVY ENDKDYPKPL
PPRGEDMEGD STEKPATDIS IGGEDAEAGG GGRTSDDESS AHISTRYSRT GVNKRSYAGM
DDNEDVPDDE CYKDPETGSR RRRKANDDDE PFEVRLKEPA EQRFPHLQKA AEQVRPTRER
VRFKAFGTQL SESSASANSL KKFLSRVDKI LEAVEELDLL TPMVKGSSLK KMDGDVINVD
EDEAEAEEAA VALADASVPA EATIAPSDLA ELSKDVAKLK STGSANQVPM DRLLKLLTLL
LLNVRDGANV TPTSSQDASD RRESRLWREI AMERVTRSVQ SSLISITLMT SKDMPREIYL
EDVIEQVVQV TRFQLSNCIY PEYDPAYRVE NTAKDNQNSI KSRRARERDI HKSTAIVHLY
YRLVEIVSSL AELVNMQRLT DSLVLALSSL GVSAFFVENV TELQLAALKL VTGIFSQYEA
HRNLIVEDII ASIARLPSSK KNLRAYRKQR PSVGIEKKGC EEVLPFVSDR VPLAFLGFVV
HPGILHLQQP LLYKAATSVE GCLVCSGRAI DVGFVQLVLL DEQSVDGCVV VIEPVLVLTT
LNSEESIQMF TALALLLVQS VIELPTRPTD QKASSANADE ISAAAAANNP DPSKAKPSRP
DDEVLVTSSY QTALRTAHSF LAVFLKKSTT RGEDDYRIIF ENFVNDLLLT VNKPEWPAAE
VMLSLLGSLL VQQFNNKSLD QAIRVTSVDY LGTVASTLRH DAVTSQLKEH DIDLIIKELI
DGNQSDSEEE EASEAETTEA KSDLEERKKK ARRKEEEEQE QDENKDEIKE NGLAPETKDS
KSEPVDEEAT KKTDDGEKGD IQVPSAEAVI SIDGVQKETA ANGRRHKRKS TLANSTNTPA
TDLAPSAPAE MDRILVLRDA MLDYLLEDAA NPVALYACKF YMAQWLEDCS KEVERAQRLA
NASESETGET AEAQTSSAVP QPSGRRSSRR VVPPTTSTSL SATDLAEQRR QYLMDRLRDD
PANWRLRCRA KGNRLGSSVM VNAGGTNPFS RQSEKLRVLF KGTIDYEDAY LICRYLASLR
PFSQSFDVYL SQICKLLSES SVAVRTKALR CLSAVVEADP GVLARCDIEL AVRSRLHDSS
TSVREAAVDL LGRFLVCRPE LTAQYYPMLS DRIRDTGVSV RKRVIRILRD ICIEQPDFAR
IADICVMIIR RVKDEESVKK LVNEVFQTLW FTPVREKESV KLLRKVMNIT DVVAASKETG
YEWFEQFLES LLSKEEGEKV RPVEKACVQI VECLVQNIMR LEEIPGQTNR LVACLATLHL
FTKIRPQLMV KHAMLIQPYL SIRGHGTSDA HILHYVARIL EVTVPLLEHP SETFLAQLEE
DMVRLTLRQG KIVLESCVAC LGAVVNQVSK NYSLTRDCFS RFFNALVRFK DDLTAEPEKP
ISPQIRPSIL RALFTVGLLC KHFDPNVFQR GTQPKILDQV FDTLMFFSEQ LKTDLEMRKK
ALAGLGFLCT RHHELLCGSR LCNFYHHLLQ APHPPQSTGS AANTSSRPQS DGSVELKNLV
LENLLHFFLE EERRMLEADA KCEFVLSSFS HLSLPALVSS RSDLSFAVCL CYAIISCHAC
HKEESLKIMG DVASGIGSHV AQAYLKDILE SFFSPSPSVR LTSLSVITTI LRQGLIHPVQ
TVPYLIATQT DYDPNVRFKA ETQLQEIDNK FPGFISMRAT QGVCMSFRLQ AVLHASGCLH
KTDARPDEPA AAAASVPEGT SATCTPQQTP QKTASASSTR RSTRHHNQQS QQSESENLSQ
ETVSAPTAVV PDSGGRTPAA LPVVIDYGAI RGSRNVDSDI PSALNSQLYS MLRGNRGQRR
SFLNGLLALF DDSQRLSLAR LVYVADNLAF FPYQCQEEPL FVIHHIDLTV SMNGSTLLQS
VREALFPEFK AALEAAMAAQ RAAEAESTAA AVPGISDDHP AIQQQNQQTT ASEGRQTRAE
SAAATPSKQS LFKLTASASS SSVLNVGREA TSSFNSSITS LYVDEENEDA MVTRLVSSGP
AGFAAVRNAV HASRACLLLL NLKQYLKDVY GMTDSKVQKY SPTDSSKLWE KQLTRRSGVR
FVPTLCLRSA AEEIAEVASN AIAPRAVASS DEKAVNAQPE DTQEISTEAA RALVFEFLEF
RKLILSIDPP DEDDTLDTSM NAGEVGQSLQ AGDTATDTVP TRLPPGRTLV PQTHGRSSDE
EDENSDDSNA GGASRLLLAQ SAPQRRRGAS GSAIATRSAR VTRPTPTKRR STRQKRMRVV
LSSDEDSESP FESEASDADS S
//
