ID   A0A183SWG0_SCHSO        Unreviewed;       638 AA.
AC   A0A183SWG0;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 23.
DE   SubName: Full=Anion exchange protein {ECO:0000313|WBParaSite:SSLN_0000889301-mRNA-1};
OS   Schistocephalus solidus (Tapeworm).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Cestoda;
OC   Eucestoda; Diphyllobothriidea; Diphyllobothriidae; Schistocephalus.
OX   NCBI_TaxID=70667 {ECO:0000313|Proteomes:UP000050788, ECO:0000313|WBParaSite:SSLN_0000889301-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:SSLN_0000889301-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC       Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC       {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC       {ECO:0000256|ARBA:ARBA00004141}.
CC   -!- SIMILARITY: Belongs to the anion exchanger (TC 2.A.31) family.
CC       {ECO:0000256|ARBA:ARBA00010993}.
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DR   AlphaFoldDB; A0A183SWG0; -.
DR   WBParaSite; SSLN_0000889301-mRNA-1; SSLN_0000889301-mRNA-1; SSLN_0000889301.
DR   Proteomes; UP000050788; Unplaced.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0008509; F:monoatomic anion transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0005452; F:solute:inorganic anion antiporter activity; IEA:InterPro.
DR   Gene3D; 1.10.287.570; Helical hairpin bin; 1.
DR   InterPro; IPR013769; Band3_cytoplasmic_dom.
DR   InterPro; IPR011531; HCO3_transpt-like_TM_dom.
DR   InterPro; IPR003020; HCO3_transpt_euk.
DR   InterPro; IPR016152; PTrfase/Anion_transptr.
DR   PANTHER; PTHR11453; ANION EXCHANGE PROTEIN; 1.
DR   PANTHER; PTHR11453:SF47; ANION EXCHANGE PROTEIN; 1.
DR   Pfam; PF07565; Band_3_cyto; 1.
DR   Pfam; PF00955; HCO3_cotransp; 2.
DR   SUPFAM; SSF55804; Phoshotransferase/anion transport protein; 1.
PE   3: Inferred from homology;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Ion transport {ECO:0000256|ARBA:ARBA00023065};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        173..192
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        199..218
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        253..275
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        287..305
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        325..346
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        387..408
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        428..447
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        486..506
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        512..536
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        556..576
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        582..599
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          4..121
FT                   /note="Band 3 cytoplasmic"
FT                   /evidence="ECO:0000259|Pfam:PF07565"
FT   DOMAIN          151..308
FT                   /note="Bicarbonate transporter-like transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF00955"
FT   DOMAIN          320..562
FT                   /note="Bicarbonate transporter-like transmembrane"
FT                   /evidence="ECO:0000259|Pfam:PF00955"
SQ   SEQUENCE   638 AA;  71058 MW;  7C099803F6BEC432 CRC64;
     LKRTNMHLNA CLPEGTEACC VLTGYVQELK QHVYVLTRLK TAIDGLGMVE VNNPLRFIVL
     FLTSDRSQVE AFSELGRCFA LLMQDSAFRM TAYAAHDTNV LIQAMGNYLQ TTVVLPKSAI
     KSAIVGETGL ALPQTDPVQF DRTDLSNMWV HRYCSDFKDA FEKDNIATVL SSIPFVFFVV
     FGPTITMGNL YVKEVNPLVN LELCIVSCGF FTATYALLSG QPAATVGPSG PCFIFEGITA
     QLSRSLHVPF SNFRFWIGIY TAISGLILIG LNFSNLAKYA RRSLEELFSS FVAFYFILKA
     LFALFKVRVC MYEVQNPSTH SARYWVGAFN VPLGMLFVTV MERIIFSSYQ LPTLNIPKFN
     EISVSSWIRI VNISTVTDFG SISAPMLHAL SAVIGLFFTL LIFCETMLNS ITALKPKAKK
     PSPVVMDHIL TNVAFPLISV FLGWPFMSGV PVRTIANTMA LVKLEPHPPP GKPAEIISLV
     EQRVNLLIVG LLVMCAVALG DILRFIPVAA LYGMFLFVGM SGLRGLDLTN SISALLCRRK
     YWGRWEFLSN LPKQQLAVFT LIRFCELSIL IAIMIIAEFS SASWISFAFP LIIIISALIR
     EFVLPRWRWL AVYLEIVRFI NLTFSATRVA DLLDSLGV
//