ID   A0A183VNC6_TRIRE        Unreviewed;       888 AA.
AC   A0A183VNC6;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 33.
DE   RecName: Full=Protein-tyrosine-phosphatase {ECO:0008006|Google:ProtNLM};
GN   ORFNames=TRE_LOCUS1982 {ECO:0000313|EMBL:VDP97861.1};
OS   Trichobilharzia regenti (Nasal bird schistosome).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Trichobilharzia.
OX   NCBI_TaxID=157069 {ECO:0000313|WBParaSite:TRE_0000198401-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:TRE_0000198401-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDP97861.1, ECO:0000313|Proteomes:UP000280995}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UZAO01048434; VDP97861.1; -; Genomic_DNA.
DR   STRING; 157069.A0A183VNC6; -.
DR   WBParaSite; TRE_0000198401-mRNA-1; TRE_0000198401-mRNA-1; TRE_0000198401.
DR   Proteomes; UP000280995; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
DR   GO; GO:0016311; P:dephosphorylation; IEA:InterPro.
DR   Gene3D; 3.90.190.10; Protein tyrosine phosphatase superfamily; 2.
DR   InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR   InterPro; IPR000242; PTP_cat.
DR   InterPro; IPR016130; Tyr_Pase_AS.
DR   InterPro; IPR003595; Tyr_Pase_cat.
DR   InterPro; IPR000387; Tyr_Pase_dom.
DR   PANTHER; PTHR19134; RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE; 1.
DR   PANTHER; PTHR19134:SF531; TYROSINE-PROTEIN PHOSPHATASE LAR; 1.
DR   Pfam; PF00102; Y_phosphatase; 2.
DR   PRINTS; PR00700; PRTYPHPHTASE.
DR   SMART; SM00194; PTPc; 2.
DR   SMART; SM00404; PTPc_motif; 2.
DR   SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 2.
DR   PROSITE; PS00383; TYR_PHOSPHATASE_1; 2.
DR   PROSITE; PS50056; TYR_PHOSPHATASE_2; 2.
DR   PROSITE; PS50055; TYR_PHOSPHATASE_PTP; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000280995};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        99..125
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          211..554
FT                   /note="Tyrosine-protein phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS50055"
FT   DOMAIN          489..545
FT                   /note="Tyrosine specific protein phosphatases"
FT                   /evidence="ECO:0000259|PROSITE:PS50056"
FT   DOMAIN          617..879
FT                   /note="Tyrosine-protein phosphatase"
FT                   /evidence="ECO:0000259|PROSITE:PS50055"
FT   DOMAIN          794..870
FT                   /note="Tyrosine specific protein phosphatases"
FT                   /evidence="ECO:0000259|PROSITE:PS50056"
SQ   SEQUENCE   888 AA;  101773 MW;  173C6DA32A8BDB05 CRC64;
     MLPLGGNTNH ILLDSNSLDY NRGQTLEDEE NLTTDLCTPS LWSVDFQPDQ AISYTDKQIG
     DMYASEPKEN DVRQNSAMQI SNSNTQSEFF AKLAGSTDFF TITLIVVIAS LSILATVCTA
     VGCFLRKRRT KPMDNDMSIT LTPSDGMLKT PLMPQSVQNF SGANGAVEHD QMDPETPDNP
     TPIHTPVRSA IPISRLPEHV AMLKRDSGIA ISDEYESIET RTDLTWKHAN LEENRPKNRY
     ANVIAYDQSR VILSEIGHVP GSDYINANFI DGYQKKNAYI ATQGPLPGTF YDFWRMVWEQ
     NSRVIVMMTR LEERARIKCD QYWPNRGREI FTYQQQQQCQ QQEHNTKTNY NINYASVPTY
     TVITKDIQEF AYYTLRTFTL QRNNETNLVD PESSGLNQHH RITDPNSSIE EREIKQFQFT
     AWPDYGTPDY PQPLLLFIRR VSQIRSHLIH QMQQERLIND EKHNSRDLKL TQPNDTRNSL
     NLNLSDEIGP LIVHCSAGVG RTGAFIVIDS QLERLKHENS VDIFGAVCRM RAQRNFMVQT
     EEQYAFLYDV FVEAAEVHGT EVTAHGLYNH VVKLRQPVPT CVLARYNLLP NGLQEEYINS
     INTNNNQLAS SIKISSLELE FKRLNRNLLN KRQISTALTN ENRMKNRDGD VLPYESNRVC
     LPVIRGITGS DYINASYIDG YRKNRAYIAT QTPLPSTVDD FWRLIWECNS PIIVAFCDNR
     EANLVPADVN QYWPSNRSTR YQKIMVEPMV EYNMPHFILR EFRLTDTTDG QSRTLRQFQL
     HGWPNDSIVP KSAEAIIDLI GQVHKTQTQF GQDGPITVHC NSGSGRTGVF ICLSLLLDRM
     RCEGMVDMFL ITRMLRTQRI NTIQTSDQYA FCYAATLEYL ASFDHYMS
//