ID   A0A183VR21_TRIRE        Unreviewed;       432 AA.
AC   A0A183VR21;
DT   07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT   07-SEP-2016, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   SubName: Full=PI3K/PI4K domain-containing protein {ECO:0000313|WBParaSite:TRE_0000292901-mRNA-1};
GN   ORFNames=TRE_LOCUS2927 {ECO:0000313|EMBL:VDP98806.1};
OS   Trichobilharzia regenti (Nasal bird schistosome).
OC   Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC   Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Trichobilharzia.
OX   NCBI_TaxID=157069 {ECO:0000313|WBParaSite:TRE_0000292901-mRNA-1};
RN   [1] {ECO:0000313|WBParaSite:TRE_0000292901-mRNA-1}
RP   IDENTIFICATION.
RG   WormBaseParasite;
RL   Submitted (JUN-2016) to UniProtKB.
RN   [2] {ECO:0000313|EMBL:VDP98806.1, ECO:0000313|Proteomes:UP000280995}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG   Pathogen Informatics;
RL   Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; UZAO01049907; VDP98806.1; -; Genomic_DNA.
DR   STRING; 157069.A0A183VR21; -.
DR   WBParaSite; TRE_0000292901-mRNA-1; TRE_0000292901-mRNA-1; TRE_0000292901.
DR   Proteomes; UP000280995; Unassembled WGS sequence.
DR   GO; GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
DR   GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1070.11; Phosphatidylinositol 3-/4-kinase, catalytic domain; 1.
DR   InterPro; IPR011009; Kinase-like_dom_sf.
DR   InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR   InterPro; IPR036940; PI3/4_kinase_cat_sf.
DR   PANTHER; PTHR11139; ATAXIA TELANGIECTASIA MUTATED ATM -RELATED; 1.
DR   PANTHER; PTHR11139:SF9; SERINE_THREONINE-PROTEIN KINASE MTOR; 1.
DR   Pfam; PF00454; PI3_PI4_kinase; 1.
DR   SMART; SM00146; PI3Kc; 1.
DR   SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR   PROSITE; PS50290; PI3_4_KINASE_3; 1.
PE   4: Predicted;
KW   Kinase {ECO:0000256|ARBA:ARBA00022777};
KW   Reference proteome {ECO:0000313|Proteomes:UP000280995};
KW   Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT   DOMAIN          1..234
FT                   /note="PI3K/PI4K catalytic"
FT                   /evidence="ECO:0000259|PROSITE:PS50290"
FT   REGION          321..346
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   432 AA;  47568 MW;  0C989D3C8910CA39 CRC64;
     MSIIPLSTYT GLIGWVPNSD TFHNLIRDYR EKADVVLNKE NREMLRLAPD FDRLNVIQKT
     EIFEAGLRES PGRDLANILW LKSHSSEAWF ERRTTFTRSM ATIHPSNIML SRETGKVIHI
     DFGDCFEVAT LREKFPEKVP FRLTRMIIAA MEVTGIDGVY RHTCEMVMSL MRSNRESLLA
     VLEAFIHDPL LQWVLHENRK EFNHLENKLD DGGGAGAGGG GALAVGGGAG GGQVYPTGQM
     NANATGIAVA AAAAMATNCL TAGGGGGAGG GAGGQAGLGT NNQVVQPKPQ TNRNLDYAYR
     HGLLTHHQNT PHRVIDKTTG QQIPQGHCHP QQLQHQPSTQ QHANRRMNTS KKVFTNPNHP
     DSVSLRDPQK VNPWRHHLCN GPWFGCYETA KRLRRQTESG HIVIERHGLQ GFIFSAKPPS
     TEDSSIDSEG NV
//