ID A0A183VZA9_TRIRE Unreviewed; 549 AA.
AC A0A183VZA9;
DT 07-SEP-2016, integrated into UniProtKB/TrEMBL.
DT 07-SEP-2016, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=G_PROTEIN_RECEP_F1_2 domain-containing protein {ECO:0000313|WBParaSite:TRE_0000581901-mRNA-1, ECO:0000313|WBParaSite:TREG1_98810.1};
GN ORFNames=TRE_LOCUS5815 {ECO:0000313|EMBL:VDQ01695.1};
OS Trichobilharzia regenti (Nasal bird schistosome).
OC Eukaryota; Metazoa; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda;
OC Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Trichobilharzia.
OX NCBI_TaxID=157069 {ECO:0000313|WBParaSite:TRE_0000581901-mRNA-1};
RN [1] {ECO:0000313|WBParaSite:TRE_0000581901-mRNA-1}
RP IDENTIFICATION.
RG WormBaseParasite;
RL Submitted (JUN-2016) to UniProtKB.
RN [2] {ECO:0000313|EMBL:VDQ01695.1, ECO:0000313|Proteomes:UP000280995}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RG Pathogen Informatics;
RL Submitted (NOV-2018) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the G-protein coupled receptor 1 family.
CC {ECO:0000256|RuleBase:RU000688}.
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DR EMBL; UZAO01055352; VDQ01695.1; -; Genomic_DNA.
DR STRING; 157069.A0A183VZA9; -.
DR WBParaSite; TRE_0000581901-mRNA-1; TRE_0000581901-mRNA-1; TRE_0000581901.
DR WBParaSite; TREG1_98810.1; TREG1_98810.1; TREG1_98810.
DR Proteomes; UP000050795; Unassembled WGS sequence.
DR Proteomes; UP000280995; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004930; F:G protein-coupled receptor activity; IEA:UniProtKB-KW.
DR Gene3D; 1.20.1070.10; Rhodopsin 7-helix transmembrane proteins; 2.
DR InterPro; IPR000276; GPCR_Rhodpsn.
DR InterPro; IPR017452; GPCR_Rhodpsn_7TM.
DR PANTHER; PTHR24248; ADRENERGIC RECEPTOR-RELATED G-PROTEIN COUPLED RECEPTOR; 1.
DR PANTHER; PTHR24248:SF66; OCTOPAMINE RECEPTOR BETA-2R; 1.
DR Pfam; PF00001; 7tm_1; 2.
DR PRINTS; PR00237; GPCRRHODOPSN.
DR SMART; SM01381; 7TM_GPCR_Srsx; 1.
DR SUPFAM; SSF81321; Family A G protein-coupled receptor-like; 1.
DR PROSITE; PS00237; G_PROTEIN_RECEP_F1_1; 1.
DR PROSITE; PS50262; G_PROTEIN_RECEP_F1_2; 1.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW G-protein coupled receptor {ECO:0000256|RuleBase:RU000688};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Receptor {ECO:0000256|RuleBase:RU000688};
KW Reference proteome {ECO:0000313|Proteomes:UP000280995};
KW Transducer {ECO:0000256|RuleBase:RU000688};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU000688};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 58..85
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 97..116
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..157
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 219..244
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 476..496
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 508..530
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 77..527
FT /note="G-protein coupled receptors family 1 profile"
FT /evidence="ECO:0000259|PROSITE:PS50262"
FT REGION 392..427
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 549 AA; 63304 MW; 9A5647DDA48F877B CRC64;
MNQSHLSDNN TVLGNVHNWQ KYQVDDCYVL FSKNPDSFVY KINSLANHTL LFSQSKSLVS
IMTTCFLIIS TLVIFFGNML VITAVATTKR LRRVTDLYIV SLAVADLLVS VFILPLSIVR
QSYGYWPYES HGLCLYFLSA NILLCLSSIL NLCCISVDRY IAIVHPLKYI SKRTRQTALM
MIAFAWITSF ISMLPPILSK QHHTGVGMCY IRSDTQYRIL SGVLAFCIPF PLVGFIYLQI
FWVIQHRSKA SKSSKFPSRL KEHRYGSVSI LFDLNHLGRI KKWFSTDEFK RDRLFVLHGQ
KSKSCTAYIR NNRNKNTNNS KPGISTENDM YSSDVFCQSP SCSHNNYISS PSTADISQTM
KSCPEPKEIV QISMVPKRFR IGANLVFPRE QENKKIKDEN KSSPSVSNTQ IDSKTKDDTC
ITDQSSKESE YIQTQRFKGR SRMDLKLDNS SIHINLNRNK QERQIFKREQ KTARSISIVV
GCFMICWFPF ASIYLVEGIF ECLLSEQVYM ITGWFAYLNS MCNPFIYAFC NKEYANAFKR
LLHFRKYQI
//
